Amitriptilina
Elavil
Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 5 Oct 2023
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Mantén tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
Amitriptyline may make you feel sleepy. If this happens, do not drive and do not use tools or machines. Do not drink alcohol.
Common side effects of amitriptyline include dry mouth, constipation, dizziness, sleepiness, and blurred vision.
Tell your doctor if you experience any troublesome side effects.
De un vistazo
Amitriptyline is a medicine used for nerve pain, headaches, migraines, and bedwetting.
It can cause side effects like dry mouth, constipation, and drowsiness.
Do not drive or use machines if you feel sleepy or have blurred vision.
Avoid alcohol as it can increase the risk of side effects.
Take it exactly as your doctor tells you, usually as a single dose at bedtime.
Do not stop taking it suddenly; your doctor may reduce the dose gradually.
About amitriptyline
Tipo de medicamento | Un antidepresivo tricíclico |
Usado para | Depression, nerve pain, headaches and migraine, bedwetting in children (nocturnal enuresis) |
También llamado (EE.UU.) | Elavil® |
Disponible como | Tabletas y medicina líquida oral |
What is amitriptyline used for?
Amitriptyline belongs to a group of medicines known as antidepresivos tricíclicos. It is commonly used to help ease certain types of nerve pain, and also to help prevent migrañas. It can also be used to help children with bedwetting problems.
It has been traditionally prescribed for the treatment of depression, although it is rarely used for this nowadays.
Side effects of amitriptyline
The most common side effects of amitriptyline are:
Boca seca.
Estreñimiento.
Diarrea.
Sentirse mal (náuseas).
Feeling dizzy or lightheaded - especially when standing up.
Feeling sleepy.
Visión borrosa.
Dolor estomacal.
Encontrará una lista completa en el prospecto del fabricante que se suministra con su medicamento. Los efectos no deseados a menudo mejoran a medida que su cuerpo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes persiste o se vuelve problemático.
How to manage amitriptyline side effects
Common amitriptyline side effects | ¿Qué puedo hacer si experimento esto? |
Boca seca | Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar |
Estreñimiento | Intenta comer una dieta bien equilibrada que contenga mucha fibra y bebe mucha agua cada día |
Feeling sleepy, blurred vision | No conduzca ni utilice herramientas o máquinas hasta que se sienta mejor. No consuma alcohol |
Feeling dizzy or light-headed when getting up | Getting up more slowly may help. If you begin to feel faint, sit down and wait until the feeling passes |
Feeling sick, diarrhoea, stomach pain | Stick to simple meals - avoid rich or spicy foods. Drink plenty of water to replace lost fluids |
Other side effects include feeling anxious or confused, sleeping problems, problems passing urine, tingling feelings, breast tenderness, problems when having sex, changes in appetite and weight, changes in the way things taste, ringing noise in the ears, itchy skin rash, hair loss, increased sweating, changes in heart rate or rhythm | Si alguno de estos se vuelve problemático, hable con su médico para obtener consejo |
If you experience any other symptoms which you think may be due to amitriptyline, speak with your doctor or pharmacist for further advice.
Who should not take amitriptyline?
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking amitriptyline it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes una glándula tiroides hiperactiva.
Si tienes un problema con el funcionamiento de tu hígado.
Si tienes epilepsia.
Si tienes niveles altos de azúcar en la sangre (diabetes mellitus).
Si has tenido problemas de estreñimiento.
Si tiene alguna dificultad para orinar, o si ha tenido problemas de próstata.
If you have a heart disorder or blood vessel disease.
Si alguna vez has tenido un problema de salud mental (en particular, trastorno bipolar o psicosis).
If you have increased pressure in your eyes, a condition called glaucoma.
If you have been told you have a tumour on your adrenal gland, called phaeochromocytoma.
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is especially important if you have recently taken a medicine for depression, known as a monoamine-oxidase inhibitor (MAOI).
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take amitriptyline
Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about amitriptyline and will provide you with a full list of the side effects which you may experience from taking it.
Take amitriptyline exactly as your doctor tells you to. It is usually prescribed as a single dose to be taken at bedtime, although your dose may differ from this.
The directions for taking it will be printed on the label of the pack to remind you what the doctor has said to you. If you have any questions about what dose to take, ask your pharmacist for advice.
Your doctor is likely to prescribe you a small dose when you first start taking it, and then increase your dose gradually as your body gets used to it.
Many people find if helps to swallow the tablets with a drink of water. You can take amitriptyline before or after food.
If you forget to take a dose, take one as soon as you remember. If when you remember, it is nearly time for your next dose then take your next dose when it is due but leave out the missed dose. Do not take two doses at the same time to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Intenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
If you are taking amitriptyline for depression, you may feel that it is not working for you straightaway. It can take a week or two for the effect to build up, and 4-6 weeks before you feel the full benefit. It is important that you do not stop taking it thinking it is not helping.
While you feel depressed, you may have distressing thoughts, and think about harming yourself or ending your life. If this happens, it is very important that you tell your doctor about it straightaway.
There are several types of antidepressants - each type works in a slightly different way and can have different side effects. If you find that amitriptyline does not suit you, then let your doctor know, as another antidepressant may be found that does.
Your doctor will recommend that you do not drink alcohol while you are on amitriptyline. This is because alcohol increases the risk that you will experience side effects.
Some people who take amitriptyline find that their skin becomes more sensitive to sunlight than usual. Try to avoid strong sunlight until you know how your skin reacts, or use a sun cream with a high sun protection factor. Do not use sunbeds.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because a number of medicines can increase the risk of side effects from amitriptyline, including some strong painkillers, flu remedies and antihistamines.
If you have diabetes you may need to check your blood glucose more frequently. This is because amitriptyline can alter the levels of sugar in your blood. Your doctor will advise you about this.
If you are due to have any medical treatment, tell the person carrying out the treatment that you are taking amitriptyline as it can interfere with some anaesthetics.
Continue to take amitriptyline unless your doctor tells you otherwise. Stopping treatment suddenly can sometimes cause problems and your doctor may want you to reduce your dose gradually when this becomes necessary.
How to store amitriptyline
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Never take more than the prescribed dose. Tricyclic antidepressants can be dangerous in overdose. If you suspect that you or someone else might have taken an overdose, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.
Preguntas frecuentes
Why shouldn't you take amitriptyline after 8pm?
Amitriptyline is best taken before 8pm to avoid morning grogginess. Taking it earlier helps reduce drowsy side effects the next day.
Is amitriptyline a strong sleeping pill?
Amitriptyline is not classed as a traditional sleeping pill, but at low doses it can make you feel drowsy and help with sleep problems. Doctors sometimes prescribe it off-label for insomnia, especially if pain or anxiety is also a factor.
Is amitriptyline a strong pain killer?
Amitriptyline is not a strong painkiller like opioids, but it can be very effective for certain types of long-term pain, especially nerve pain, migraines, or tension headaches.
Is amitriptyline addictive?
Amitriptyline is not addictive, but stopping suddenly may cause withdrawal symptoms. Always reduce the dose gradually under your doctor's advice.
Why does amitriptyline cause weight gain?
Amitriptyline can cause weight gain because it may increase appetite, slow down metabolism, and make you feel more tired, which can reduce activity levels. Some people also experience fluid retention. Not everyone gains weight.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can I stop taking amitriptyline if I feel better?
It is important to continue taking amitriptyline unless your doctor tells you otherwise. If you stop treatment suddenly, it can sometimes cause problems. Your doctor may want you to gradually reduce your dose when it becomes necessary to stop taking it.
Why do I need to see my doctor regularly while taking amitriptyline?
Regular appointments with your doctor are important so they can check on your progress and ensure the medication is working effectively for you.
Can amitriptyline affect my blood sugar if I have diabetes?
Yes, if you have diabetes, amitriptyline can alter the levels of sugar in your blood. Your doctor may advise you to check your blood glucose more frequently, and you should discuss this with them.
Are there any over-the-counter medicines I should avoid while taking amitriptyline?
Yes, you should check with a pharmacist if any over-the-counter medicines are suitable for you. Some medicines, including strong painkillers, flu remedies, and antihistamines, can increase the risk of side effects from amitriptyline.
What should I do if I'm going to have surgery or other medical procedures?
If you are due to have any medical treatment, you should tell the person carrying out the treatment that you are taking amitriptyline. This is important because amitriptyline can interfere with some anaesthetics.
Lecturas adicionales y referencias
- Manufacturer's PIL, Amitriptyline Tablets 10 mg, 25 mg, 50 mg; Brown and Burk UK Ltd, The electronic Medicines Compendium. Dated January 2022.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisorVer biografía completa

Dr Colin Tidy, MRCGP
Médico General, Autor Médico
MBBS, MRCGP, MRCP (Paediatrics), DCH
El Dr. Colin Tidy es un médico del NHS, con sede en Oxfordshire.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 4 de octubre de 2026
5 Oct 2023 | Última versión

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