Tabletas de melatonina para el insomnio
Adaflex, Circadin
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 30 de agosto de 2023
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Melatonin is useful in helping to promote sleep in people over the age of 55 years who have difficulty sleeping. It also helps to promote sleep in children with learning difficulties such as Autism Spectrum Disorder (ASD) and ADHD.
Take one 2 mg tablet 1-2 hours before bedtime, with a snack.
Melatonin will make you feel sleepy, so do not drive and do not use tools or machines until this effect has worn off.
De un vistazo
Melatonin is a medicine used to treat poor sleep and is available as tablets, capsules, and liquid forms.
It helps your body's natural sleep pattern, especially if your natural melatonin production has reduced.
Different brands of melatonin are prescribed for certain age groups or conditions, such as insomnia in adults over 55.
Take melatonin exactly as prescribed by your doctor, usually 1-2 hours before bedtime with food or a snack.
Do not drink alcohol with melatonin as it reduces the medicine's effectiveness.
Common side-effects can include feeling tired, headache, or indigestion.
About melatonin
Tipo de medicamento | Hypnotic (sleeping tablet) |
Usado para | Poor sleep |
También llamado | Adaflex®; Ceyesto®; Circadin®; Civasta®; Slenyto®; Syncrodin® |
Disponible como | Modified-release tablets, tablets, capsules and oral liquid medicine |
Poor sleep can mean that you have difficulty getting to sleep, or that you wake up for long periods during the night, or that you wake early, or that you do not feel refreshed in the mornings.
Insomnia is a fairly common condition, but it does not usually last for long. Melatonin is a hormone which occurs naturally in the body and is associated with the control of the body's sleep pattern. As we grow older the amount of naturally occurring melatonin in the body reduces. Taking melatonin adds to the body's natural supply and helps to promote and improve the quality of sleep.
Circadin® and Civasta® tablets are prescribed for people over the age of 55 years who have insomnia, or difficulty sleeping.
Slenyto® tablets are prescribed for poor sleep in children between the ages of 2 years and 18 years with Trastorno del Espectro Autista (TEA) or Smith-Magenis syndrome.
Adaflex® and Ceyesto® tablets are prescribed for poor sleep in children aged 6 to 17 years with ADHD. They can also be prescribed for adults who experience jet lag.
Syncrodin® tablets are prescribed for adults who experience jet lag.
Sometimes a doctor may prescribe melatonin for other groups of people with sleeping problems. If this is the case for you, the way you take melatonin and your dose may be different from the information in this leaflet. Follow your doctor's instructions carefully and ask your doctor or pharmacist if you are unsure of anything.
Before taking melatonin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking melatonin it is important that your doctor or pharmacist knows:
Si tienes algún problema con el funcionamiento de tu hígado, o con el funcionamiento de tus riñones.
If you have an autoimmune disease - a condition in which the body is attacked by its own overactive immune system. It includes conditions such as artritis reumatoide, multiple sclerosis, and lupus.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take melatonin
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about melatonin and will provide you with a full list of the side-effects which you may experience from taking it.
Take melatonin exactly as your doctor tells you to. For adults the dose is usually one 2 mg tablet daily, taken 1-2 hours before bedtime. For children with ASD the usual starting dose is 2 mg taken 30 minutes to one hour before bedtime. Your child's doctor may increase the dose slowly to get a better response.
Take the tablet with a snack or after eating some food. This will help the medicine to work later into the night. Swallow the tablet whole - do not break or crush the tablet because it is designed to release melatonin slowly over a few hours.
If you forget to take a tablet at the usual time but you remember before you go to sleep, take it when you remember. If you do not remember until the following day, just take the next dose as usual. Do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Do not take melatonin for longer than your doctor advises. It can be prescribed for up to 13 weeks for adults over 55.
Do not drink alcohol while you are taking melatonin because it will reduce the medicine's effectiveness in helping you to sleep.
Try to keep your regular appointments with your doctor. This is so your progress can be monitored.
There are some general recommendations that may help promote good sleep. Try to reduce the amount of caffeine you drink, especially in the afternoon and evening. Try to avoid eating heavy meals or drinking alcohol before bedtime. Exercise early in the day, rather than in the evening.
Can melatonin cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects but not everyone experiences them. The table below contains some of the side-effects associated with melatonin. Children may be more likely than adults to experience these side-effects. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Melatonin side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Feeling tired or sleepy | Do not drive and do not use tools or machines until these effects have worn off |
Dolor de cabeza | Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Indigestion, feeling sick (nausea), stomach ache | Mantente en alimentos simples - evita comidas ricas o picantes |
Feeling irritable or restless, mood swings, dry mouth, abnormal dreams, night sweats, dry or itchy skin, pains in the arms or legs | Si alguno de estos se vuelve problemático, hable con su médico |
If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice. Children with ASD may be more likely to experience mood swings, irritability or aggression when taking melatonin.
How to store melatonin
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
If you are having an operation or dental treatment, always tell the person carrying out the treatment which medicines you are taking.
Si compras algún medicamento, consulta con un farmacéutico que sea seguro tomarlo junto con tus otros medicamentos.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can I take melatonin if I have an autoimmune disease?
If you have an autoimmune disease, it's important that your doctor or pharmacist knows before you start taking melatonin. This is because some medicines are not suitable for people with certain conditions, and extra care may be needed.
Are there any specific lifestyle changes I can make to improve my sleep while taking melatonin?
Yes, there are several general recommendations that can help promote good sleep alongside taking melatonin. You should try to reduce your caffeine intake, especially in the afternoon and evening. It's also advisable to avoid heavy meals or alcohol before bedtime. Additionally, exercising early in the day rather than in the evening can be beneficial.
What should I do if I notice unusual side-effects in a child taking melatonin?
Some side-effects due to melatonin can be more common in children. For instance, children with Autism Spectrum Disorder (ASD) might be more prone to mood swings, irritability, or aggression. If you notice any troublesome symptoms, or any other symptoms you think might be related to the tablets, you should speak with your doctor or pharmacist for advice.
How should I store melatonin medication?
Melatonin should be stored in a cool, dry place, away from direct heat and light. It is very important to keep all medicines out of the reach and sight of children.
What should I do if I forget to take a dose of melatonin?
If you forget to take your tablet at the usual time but remember before you go to sleep, you should take it then. However, if you don't remember until the following day, simply take your next dose as usual. Do not take two doses together to compensate for a forgotten dose.
Lecturas adicionales y referencias
- Manufacturer's PIL, Circadin® 2 mg prolonged-release Tablets; Flynn Pharma Ltd, The electronic Medicines Compendium. Dated October 2021.
- Manufacturer's PIL, Slenyto® 1 mg and 5 mg prolonged release tablets; Flynn Pharma Ltd, The electronic Medicines Compendium. Dated October 2021.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Siguiente revisión prevista: 29 de agosto de 2026
30 de agosto de 2023 | Última versión

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