Cápsulas de acitretina para la psoriasis
Neotigason
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 20 Sept 2024
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Acitretin will be prescribed for you by a skin specialist doctor.
Take your doses during a mealtime. Swallow the capsule(s) with a drink of milk or water.
Avoid bright sunlight or use a high-factor sun cream (SPF 15 or greater). Do not use sunbeds.
Acitretin is harmful to unborn babies. You MUST use effective contraception if you could get pregnant.
De un vistazo
Acitretin is a retinoid medicine, similar to vitamin A.
It treats severe psoriasis and other skin conditions by helping skin grow more normally.
Take capsules once daily with food, exactly as your doctor tells you.
Women must not become pregnant during treatment and for three years afterwards.
Acitretin can make your skin more sensitive to sunlight, so protect your skin.
Common side-effects include dry skin, lips, mouth and eyes.
About acitretin
Tipo de medicamento | A retinoid medicine (similar to vitamin A) |
Usado para | Severe psoriasis and some other skin conditions |
También llamado | Neotigason® |
Disponible como | Cápsulas |
Acitretin is used to treat severe skin conditions where the surface of the skin has become thick and scaly. Normally, as new skin cells are produced, older ones are lost. If the skin cells in the outer layer of your skin multiply faster than normal, the old skin cells can build up on the surface of your skin, causing thick or scaly patches.
Acitretin is a retinoid medicine, which means simply that it is related to vitamin A. Our bodies use vitamin A to maintain a healthy skin. Acitretin helps to control conditions like psoriasis by making your skin grow more normally.
Acitretin is sometimes used as a treatment on its own but, more often, it is used alongside other preparations to help the skin's condition.
Before taking acitretin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking acitretin it is important that your doctor knows:
If you are pregnant, trying for a baby or breastfeeding. This is because you must reportado take acitretin if you think you are (or think you may be) pregnant.
Si tienes algún problema con el funcionamiento de tu hígado, o algún problema con el funcionamiento de tus riñones.
If you have high levels of fats (lipids) such as cholesterol in your blood.
Si tienes diabetes (diabetes mellitus).
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take acitretin
Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack and any other information that you are given by your doctor. The leaflets will give you more information about acitretin and will provide you with a full list of the side-effects which you could experience from taking it.
Take the capsules exactly as your doctor tells you to. Acitretin is taken once daily. Your doctor will tell you how many capsules to take and this will also be printed on the label of the pack to remind you about what the doctor said to you. Take each of your doses with a snack, or just after eating a meal. It is a good idea to swallow the capsules with a drink of water or milk.
Try to take your doses of acitretin at the same time of day each day, as this will help you to remember to take them regularly. If you forget to take a dose at the usual time, take it when you remember. If you do not remember until the following day, then miss out the forgotten dose. Do not take two doses together to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
It is important for you to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests during the treatment. The tests will check that your lipid levels are normal and that your liver remains healthy. If you are a woman, you may also need to have regular tests to confirm that you are not pregnant.
It can take 2-4 weeks before you start to feel the benefit from the capsules and it may take up to four months before you feel the maximum benefit. A course of treatment is likely to last for up to six months but occasionally it can be for longer than this.
Acitretin is harmful to unborn babies, so it is very important that you do not become pregnant while you are taking it. Your doctor will advise you about suitable contraception and this may include using more than one method. You should continue to use suitable contraception for at least three years after you finish your course of treatment. If at any time during your treatment or the three years afterwards, you think you may be pregnant, contact your doctor for advice straightaway.
If you buy any medicines, vitamins, or herbal preparations, please check with your doctor or a pharmacist that they are suitable for you to take with acitretin. This is because you must not take any other preparation which contains vitamin A.
Acitretin can cause your skin to become more sensitive to sunlight than normal. Protect your skin from sunlight even on bright but cloudy days and do not use sunbeds.
If you normally drink alcohol, please ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on this medicine.
If you have diabetes you may need to check your blood sugar (glucose) more frequently, as acitretin can affect the levels of sugar in your blood. Your doctor will advise you about this.
You must not give blood while you are on acitretin and for at least three years after you finish taking it. This is because it could cause harm to other people.
Can acitretin cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with acitretin. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common acitretin side-effects (these affect around 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Dry mouth, feeling thirsty, sore mouth | Try chewing sugar-free gum or sucking sugar-free sweets. If this continues, ask your doctor for advice |
Dry or irritated eyes, blurred vision, and reduced night vision | Take extra care when driving at night. If this becomes troublesome, speak with your doctor |
Dry skin and lips, peeling | Use a moisturising cream and lip balm regularly. After peeling, the new skin often appears more normal |
Dolor de barriga (abdominal), sensación de malestar (náuseas), diarrea | Stick to simple meals (avoid rich or spicy foods). Drink plenty of water to replace any lost fluids |
Muscle and joint pain | Let your doctor know about this so that it can be investigated |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Dry or irritated nose, nosebleeds, weak nails, swollen feet and ankles, mood changes, loss of hair and changes in hair texture | Si alguno de estos se vuelve problemático, hable con su médico |
Si experimenta cualquier otro síntoma que crea que puede deberse a las cápsulas, por favor hable con su médico o farmacéutico para obtener más consejos.
How to store acitretin
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Si va a someterse a una operación o tratamiento dental, por favor informe a la persona que realiza el tratamiento qué medicamentos está tomando o usando.
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can I take acitretin if I have diabetes?
If you have diabetes, your doctor needs to be aware of this before you start taking acitretin. You may need to monitor your blood sugar (glucose) levels more frequently, as this medication can affect them. Your doctor will provide specific advice on managing this.
How long will I need to be on acitretin treatment?
A typical course of treatment with acitretin is likely to last for up to six months. However, in some cases, your doctor may decide to extend the treatment for a longer period.
What should I do if my skin becomes very dry due to acitretin?
Dry skin and lips are common side-effects of acitretin. To manage this, you should regularly use a moisturising cream and lip balm. It's often observed that after an initial period of peeling, new skin appears more normal.
Why do I need regular blood tests while taking acitretin?
Regular blood tests are essential to monitor your progress and ensure your safety while on acitretin. These tests help your doctor check that your lipid levels (fats like cholesterol) remain normal and that your liver is functioning healthily. If you are a woman, regular tests may also be needed to confirm you are not pregnant.
Can I use sunbeds while taking acitretin?
No, you must not use sunbeds while taking acitretin. This medication can make your skin much more sensitive to sunlight, so it's important to protect your skin from the sun, even on bright but cloudy days.
What kind of drinks should I take with acitretin capsules?
It is a good idea to swallow acitretin capsules with a drink of water or milk. This should be done with a snack or just after eating a meal.
Lecturas adicionales y referencias
- Manufacturer's PIL, Acitretin 10 mg and 25 mg Capsules; Genus Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated December 2023.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Next review due: 25 Sept 2027
20 Sept 2024 | Última versión

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