Abiraterona para el cáncer de próstata
Zytiga
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 18 May 2024
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The usual dose is two 500 mg tablets taken together, once a day. Swallow the tablets whole, with water.
Take the tablets when your stomach is empty. This means taking your dose at least an hour before a mealtime, or waiting for two hours afterwards.
You will also be prescribed another medicine (either prednisone or prednisolone) to take alongside abiraterone. It is important that you take it regularly every day.
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About abiraterone
Tipo de medicamento | An anti-androgen medicine |
Utilizado para | Advanced prostate cancer |
También llamado | Zytiga® |
Disponible como | Tabletas |
In some men with prostate cancer, the cancer cells spread to parts of the body other than the prostate. When this happens, it is referred to as late, advanced or metastatic prostate cancer. Treatment options for this type of cancer typically include hormone treatment, surgery, radiotherapy and chemotherapy.
Abiraterone is a hormone treatment - it belongs to a group of medicines known as anti-androgens. This means that it reduces the amount of male sex hormones (called androgens) that your body produces. In prostate cancer, androgens are produced by your testicles (testes), by your adrenal glands, and in the tumour cells. Abiraterone reduces the amount of androgens produced by each of these, and this slows the growth of the cancer.
Abiraterone will be prescribed for you alongside another medicine, either prednisone or prednisolone. These medicines reduce the risk of unwanted effects from abiraterone treatment.
Before taking abiraterone
Sometimes a medicine may only be used in people with certain conditions if extra care is taken. For this reason, before you start taking abiraterone it is important that your doctor knows:
If you have been told you have high blood pressure, or low levels of potassium in your blood.
Si tiene problemas de corazón o de vasos sanguíneos.
Si tiene diabetes.
Si tiene problemas renales o hepáticos.
Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
Si alguna vez ha tenido una reacción alérgica a un medicamento.
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How to take abiraterone
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about abiraterone and will provide you with a full list of the side-effects which you may experience from taking it.
Take abiraterone exactly as your doctor tells you to. The usual dose is two 500 mg tablets (1000 mg in total) taken together, once a day. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.
You must take the tablets when your stomach is empty. This means that you should take abiraterone at least an hour before a mealtime, or wait until at least two hours after you have eaten. This is because taking abiraterone with food will increase the amount of the medicine in your blood in a way that isn't predictable, and this is likely to cause side-effects.
Take the tablets with a drink of water. Swallow the tablets whole - do not crush or break the tablets in order to swallow them.
Try to take abiraterone at the same time of day each day as this will help you to remember to take your doses regularly.
If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the forgotten dose. Do not take two doses together to make up for a missed dose.
Aproveche al máximo su tratamiento
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests to check on the amount of potassium in your blood and how well your liver is working. Your doctor will also want to check your blood pressure routinely.
It is important that you continue to take the prednisone or prednisolone tablets that you will be prescribed alongside abiraterone. You should take these tablets regularly every day. Do not stop taking them unless your doctor tells you to.
If you have diabetes you will need to check your blood glucose more frequently as these tablets can increase the level of sugar in your blood. Your doctor will advise you about this.
If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is important because your dose of prednisone or prednisolone may need to be increased for a short while.
Abiraterone may harm an unborn child. This means that if you are having sex with a woman who could become pregnant, you must use a condom along with another effective birth control method. If you are having sex with a woman who is already pregnant, you must use a condom to protect the unborn child.
Si compra algún medicamento, compruebe con un farmacéutico que es seguro tomarlo con sus otros medicamentos.
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Can abiraterone cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with abiraterone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if you experience any symptoms which you think may be due to abiraterone.
Very common abiraterone side-effects (these affect more than 1 in 10 men) | ¿Qué puedo hacer si me ocurre esto? |
Feeling pain on passing urine or needing to pass urine more frequently | These may be signs that you have a urinary tract infection |
Swollen legs, feet, or ankles (due to fluid retention) | Keep your feet elevated as much as possible |
Diarrea | Beber mucha agua |
High blood pressure, low levels of potassium in your blood, increased levels of fats (triglycerides) in your blood, changes to your liver function test results | Your doctor will be monitoring your progress and will check for these |
Common abiraterone side-effects (these affect fewer than 1 in 10 men) | ¿Qué puedo hacer si me ocurre esto? |
Chest pain, feeling of a fast heartbeat, other heart problems | Informe a su médico |
Indigestión | Coma alimentos sencillos: evite las comidas ricas o picantes. |
Infections, muscle pain, skin rash, blood in your urine | Informe a su médico |
How to store abiraterone
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Zytiga® 500 mg tablets; Janssen-Cilag Ltd, The electronic Medicines Compendium. Dated September 2021.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Next review due: 24 Apr 2027
18 May 2024 | Latest version

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