Pilocarpine tablets
Salagen
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 5 Feb 2025
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Take pilocarpine during a meal. Swallow the tablet with a large glass of water.
The tablets may reduce your ability to see clearly in poor lighting. Do not drive at night if you are affected.
The most common side-effects include headache, sweating, flu-like symptoms and passing urine more frequently.
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About pilocarpine
Tipo de medicamento | A cholinergic medicine |
Usado para | Dry mouth after radiotherapy; dry mouth and dry eyes in Sjögren's syndrome |
También llamado | Salagen® |
Disponible como | Comprimidos |
Pilocarpine is prescribed to relieve boca seca (sometimes called xerostomia) brought on by radiotherapy to the head or neck.
Pilocarpine can also be used to relieve some of the symptoms of Síndrome de Sjögren. Sjögren's syndrome can cause various symptoms, the most common being dry eyes and dry mouth. These symptoms are due to lack of secretions from glands in your body.
Pilocarpine tablets stimulate your glands to produce more saliva and tears.
Before taking pilocarpine
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking pilocarpine it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes una afección cardíaca o enfermedad de los vasos sanguíneos.
If you have a problem with the way your kidneys work, or a problem with the way your liver works.
If you have asthma, COPD, or any other breathing problem.
If you have a stomach ulcer, gallstones, or a problem with your bile duct.
If you have an eye condition such as increased pressure in your eye (glaucoma), or inflammation of the iris of your eye (iritis).
If you get confused easily.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take pilocarpine
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pilocarpine, and will also provide you with a full list of side-effects which you could experience from taking it.
Your doctor will tell you how often to take the tablets - take them exactly as your doctor directs. As a guide:
If you are taking pilocarpine following radiotherapy, it is likely you will be prescribed one tablet three times daily to begin with. Take your doses during (or straight after) a meal, and make sure you take your last dose of the day with your evening meal.
If you are taking pilocarpine because you have Sjögren's syndrome, the usual dose is one tablet four times daily. Take a tablet with each of your three main meals, and also one at bedtime. Although these are the usual starting doses for people taking pilocarpine, your doctor may increase your dose if it is appropriate for you.
Every time you take a tablet, drink a large glass of water with it. This is to prevent you from becoming dehydrated, as pilocarpine can make you sweat more than usual.
If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose, don't take the forgotten dose but instead wait and take the next dose as normal. Do not take two doses together to make up for the missed dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoIntenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
If after taking pilocarpine for a couple of months you feel that your condition has not greatly improved, you should let your doctor know about this. Pilocarpine will not be effective if the glands in your mouth or eyes cannot be sufficiently stimulated to produce more saliva or tears.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking pilocarpine.
If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take alongside pilocarpine.
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Can pilocarpine cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with pilocarpine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Common and very common pilocarpine side-effects (some can affect more than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Increased sweating and flushing | Take care not to become overheated during exercise or hot weather. Drink several large glasses of water every day |
Blurred vision, eye irritation or pain, watery eyes | Do not drive and do not use tools or machines if you cannot see clearly (particularly at night or if you have difficulty seeing in poor lighting) |
Diarrhoea, constipation, tummy ache (abdominal pain) | Try to eat a well-balanced diet. Drink plenty of water |
Indigestion, feeling sick (nausea) or being sick (vomiting) | Eat simple foods - avoid rich or spicy meals |
Feeling dizzy or weak | Sit down for a few minutes until you feel better. Do not drive and do not use tools or machines while affected |
Increased frequency of passing urine, high blood pressure, the sensation of having a 'thumping' heart (palpitations), flu-like symptoms, runny nose, allergic reactions such as skin rash and itchiness | Si alguno de estos se vuelve problemático, hable con su médico |
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store pilocarpine
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Salagen® 5 mg Film Coated Tablets; Norgine Limited, The electronic Medicines Compendium. Dated April 2023.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 5 Feb 2028
5 Feb 2025 | Última versión

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