Molnupiravir para la enfermedad de COVID-19
Lagevrio
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 15 Dic 2024
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Molnupiravir is given to adults aged over 18 years when they have tested positive for COVID-19 and have at least one risk factor for developing severe illness.
Treatment should be started as soon as possible after diagnosis and within the first five days of symptoms.
The most common side-effects are feeling sick (nausea) and diarrhoea.
De un vistazo
Molnupiravir is an antiviral medicine for adults with mild to moderate COVID-19.
It helps stop the COVID-19 virus from spreading quickly in the body.
It is used for people at high risk of severe COVID-19, including those with certain long-term conditions.
Take four capsules every 12 hours for five days, swallowing them whole with water.
Start treatment as soon as possible after symptoms begin or after a positive test.
Common side-effects can include diarrhoea, feeling sick, or dizziness.
About molnupiravir
Tipo de medicamento | Agente antiviral |
Usado para | Treatment of mild to moderate COVID-19 disease in adults |
También llamado | Lagevrio® |
Disponible como | Cápsulas |
Molnupiravir is an antiviral agent that works by combining with viral RNA to stop the virus particles from replicating. If a virus can't replicate it won't be able to infect other cells in the body and the infection won't spread as quickly. Molnupiravir can reduce the severity of viral infections such as COVID-19.
Molnupiravir is used for adults who have tested positive for COVID-19 and have at least one risk factor for severe disease. Taking molnupiravir as soon as possible once COVID-19 symptoms have started can lower your risk of being severely ill or requiring hospitalisation.
People at high risk of severe COVID-19 disease include those with medical conditions such as long-term heart, lung, liver, kidney or nerve problems, people with diabetes and people with weakened immune systems.
Before taking molnupiravir capsules
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking molnupiravir it is important that your doctor knows:
Si estás embarazada, intentando concebir o amamantando.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
How to take molnupiravir capsules
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about molnupiravir and a full list of side-effects which you may experience from taking it.
The usual dose of molnupiravir is four capsules (800 mg) taken every twelve hours for five days. Make sure you complete the course even if you are feeling better.
Swallow the capsules whole with a drink of water. Do not open, crush or chew the capsules.
It is not important whether you take molnupiravir capsules before or after food.
If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose. In which case, leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Treatment with molnupiravir should be started within the first five days of COVID-19 symptoms or as soon as possible after a positive COVID-19 test result.
Make sure you complete the full course of treatment even if you start to feel better or do not feel unwell.
Help your body fight the infection by drinking plenty of water, eating sensibly and getting plenty of rest.
The best way to protect yourself from COVID-19 is through vaccination. Ensure your vaccinations are up to date in line with national guidance.
Can molnupiravir cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with molnupiravir. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common molnupiravir side-effects (affecting fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Diarrea | Bebe mucha agua para reponer los líquidos perdidos |
Sentirse mal (náuseas) | Stick to simple foods. Try taking your doses with something to eat if you are not already doing so |
Mareo | Do not drive and do not use tools or machines if affected |
Importante: In rare cases this medicine may cause a serious allergic reaction. Seek urgent medical attention if you develop a red, itchy skin rash and any difficulties with your breathing, including swelling of the face, lips or tongue. Taking an antihistamine may help slow the reaction whilst you are waiting for treatment.
Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.
How to store molnupiravir capsules
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is the age range for taking molnupiravir?
Molnupiravir is specifically used for adults aged 18 and over who have tested positive for COVID-19.
Why is it important to complete the full five-day course of molnupiravir, even if I feel better?
Completing the full course of treatment helps ensure the medication effectively stops the virus from replicating, which can reduce the severity of the infection and lower your risk of being severely ill or requiring hospitalisation. It's crucial to finish the entire course to give the medicine the best chance to work, even if your symptoms improve.
What should I do if I accidentally take two doses of molnupiravir at once?
You should never take two doses together to make up for a missed dose. If you suspect you or someone else might have taken an overdose of this medicine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
What are the common symptoms of a severe allergic reaction to molnupiravir?
Signs of a serious allergic reaction include a red, itchy skin rash, difficulties with your breathing, and swelling of the face, lips, or tongue. If you experience any of these symptoms, you should seek urgent medical attention.
Does molnupiravir interact with any other medications I might be taking?
Before starting molnupiravir, it's important to inform your doctor about all other medicines you are currently taking. This includes any over-the-counter medicines, as well as herbal and complementary medicines. Your doctor needs this information to ensure molnupiravir is suitable for you and to check for potential interactions.
Lecturas adicionales y referencias
- Manufacturer's PIL, Lagevrio® 200 mg hard capsules; Merck Sharp and Dohme (UK) Ltd, The electronic Medicines Compendium. Dated July 2024.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 15 de diciembre de 2027
15 Dic 2024 | Última versión

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