Molnupiravir for COVID-19 disease
Lagevrio
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 15 Dec 2024
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Molnupiravir is given to adults aged over 18 years when they have tested positive for COVID-19 and have at least one risk factor for developing severe illness.
Treatment should be started as soon as possible after diagnosis and within the first five days of symptoms.
The most common side-effects are feeling sick (nausea) and diarrhoea.
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About molnupiravir
Tipo de medicamento | Antiviral agent |
Usado para | Treatment of mild to moderate COVID-19 disease in adults |
También llamado | Lagevrio® |
Disponible como | Cápsulas |
Molnupiravir is an antiviral agent that works by combining with viral RNA to stop the virus particles from replicating. If a virus can't replicate it won't be able to infect other cells in the body and the infection won't spread as quickly. Molnupiravir can reduce the severity of viral infections such as COVID-19.
Molnupiravir is used for adults who have tested positive for COVID-19 and have at least one risk factor for severe disease. Taking molnupiravir as soon as possible once COVID-19 symptoms have started can lower your risk of being severely ill or requiring hospitalisation.
People at high risk of severe COVID-19 disease include those with medical conditions such as long-term heart, lung, liver, kidney or nerve problems, people with diabetes and people with weakened immune systems.
Before taking molnupiravir capsules
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking molnupiravir it is important that your doctor knows:
Si estás embarazada, intentando concebir o amamantando.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
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How to take molnupiravir capsules
Volver al contenidoBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about molnupiravir and a full list of side-effects which you may experience from taking it.
The usual dose of molnupiravir is four capsules (800 mg) taken every twelve hours for five days. Make sure you complete the course even if you are feeling better.
Swallow the capsules whole with a drink of water. Do not open, crush or chew the capsules.
It is not important whether you take molnupiravir capsules before or after food.
If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose. In which case, leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoTreatment with molnupiravir should be started within the first five days of COVID-19 symptoms or as soon as possible after a positive COVID-19 test result.
Make sure you complete the full course of treatment even if you start to feel better or do not feel unwell.
Help your body fight the infection by drinking plenty of water, eating sensibly and getting plenty of rest.
The best way to protect yourself from COVID-19 is through vaccination. Ensure your vaccinations are up to date in line with national guidance.
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Can molnupiravir cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with molnupiravir. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common molnupiravir side-effects (affecting fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Diarrea | Bebe mucha agua para reponer los líquidos perdidos |
Sentirse mal (náuseas) | Stick to simple foods. Try taking your doses with something to eat if you are not already doing so |
Mareo | Do not drive and do not use tools or machines if affected |
Importante: In rare cases this medicine may cause a serious allergic reaction. Seek urgent medical attention if you develop a red, itchy skin rash and any difficulties with your breathing, including swelling of the face, lips or tongue. Taking an antihistamine may help slow the reaction whilst you are waiting for treatment.
Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.
How to store molnupiravir capsules
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de sitio web de la Tarjeta Amarilla.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Lagevrio® 200 mg hard capsules; Merck Sharp and Dohme (UK) Ltd, The electronic Medicines Compendium. Dated July 2024.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 15 de diciembre de 2027
15 Dec 2024 | Última versión

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