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Lubiprostona para el estreñimiento

Amitiza

Clinical author's note Michael Stewart 24/8/2020: Amitiza® capsules were discontinued in the UK in January 2019. At the time of review there are no branded or generic products containing lubiprostone available in the UK. Lubiprostone may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Take one capsule twice daily for at least two weeks.

Take the capsules with food.

The most common side-effects are feeling sick, diarrhoea and headache.

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About lubiprostone

Tipo de medicamento

A chloride-channel activator

Usado para

Estreñimiento

También llamado

Amitiza® (discontinued)

Disponible como

Cápsulas

Estreñimiento en adultos is a common problem. It means either going to the toilet less often than usual to empty the bowels, or passing hard or painful stools when you do go. It can be caused by not eating enough fibre or not drinking enough fluids, or a lack of exercise or movement (such as being ill in bed). It can also be a side-effect of certain medicines (such as some painkillers), or related to an underlying medical condition. In many cases, the cause is not clear.

Lubiprostone helps to increase secretion of fluid into the bowel. This increases the movement of the bowels, making stools easier to pass. It is helpful for people for whom constipation remains a problem despite recommended changes to lifestyle or diet.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lubiprostone it is important that your doctor knows:

  • Si estás embarazada o amamantando.

  • Si estás tan estreñido que crees que puedes tener una obstrucción.

  • Si tienes algún problema con el funcionamiento de tu hígado.

  • Si tienes presión arterial baja (hipotensión).

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

  • Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about lubiprostone and a full list of the side-effects which you may experience from taking it.

  • Take lubiprostone exactly as your doctor tells you to. The usual dose is one capsule twice daily. A course of treatment lasts for two to four weeks. Swallow the capsule with a drink of water after a meal, or with a snack. The ideal times to take the capsules are after breakfast and after supper.

  • If you forget to take a dose, leave out the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

  • Remember to keep any regular appointments with your doctor. This is so your doctor can check on your progress.

  • If you have been taking lubiprostone for two weeks and have not noticed any improvement in your symptoms, let your doctor know.

  • Una dieta saludable que contenga fibra (panes y cereales integrales, salvado, frutas y verduras de hoja verde) con varios vasos de agua al día y ejercicio diario son importantes para mantener una función intestinal saludable.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with lubiprostone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common lubiprostone side-effects (these affect more than 1 in 10 people)


¿Qué puedo hacer si experimento esto?

Sentirse mal (náuseas)

Make sure you take the capsules during a meal

Common lubiprostone side-effects

(estos afectan a menos de 1 de cada 10 personas)

¿Qué puedo hacer si experimento esto?

Diarrea

Drink plenty of water. If the diarrhoea is severe, let your doctor know

Dolor de cabeza

Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico

Chest tightness, feeling short of breath

Let your doctor know about this so that your treatment can be reviewed

Sensación de mareo

No conduzca ni utilice herramientas o máquinas mientras se sienta mareado

Increased sweating, feeling flushed, swollen feet or ankles, stomach upset

Si es problemático, hable con su médico

If you experience any other symptoms which you think may be due to the capsules, speak with your doctor or pharmacist for further advice.

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Store in a cool, dry place, away from direct heat and light. The capsules can absorb moisture from the air so it is important to keep them in their original container to keep them dry. Do not keep the capsules for longer than four weeks after the container is first opened.

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.

Si compras algún medicamento, siempre consulta con un farmacéutico para asegurarte de que sean adecuados para tomar junto con tus otros medicamentos.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

verificador de síntomas

¿Inseguro sobre mezclar medicamentos?

Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.

Lecturas adicionales y referencias

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • Próxima revisión: 18 de septiembre de 2026
  • 19 Sept 2023 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por pares por

    Sid Dajani
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