Tabletas de co-fenótropo para la diarrea
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 27 Abr 2023
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The usual dose for acute diarrhoea in an adult is four tablets to start with, followed by two tablets every six hours until the diarrhoea is controlled. Do not take more than 10 tablets in 24 hours.
When you have diarrhoea it is important that you have lots of water to drink to prevent you from becoming lacking in fluid in the body (dehydrated). Eat as normally as possible, as soon as you feel able.
If your symptoms continue for more than 48 hours, speak with a doctor for advice if you have not already done so.
Co-phenotrope must not be taken by children under 16 years of age unless prescribed by a doctor.
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Co-phenotrope is a medicine used to treat sudden-onset diarrhoea.
It works by slowing down your bowel activity so contents pass through more slowly.
For adults, the usual starting dose is four tablets, then two tablets every six hours.
Do not take more than 10 tablets in 24 hours.
Drink plenty of fluids to prevent dehydration while taking this medicine.
Speak to a doctor if your symptoms worsen or do not improve within 48 hours.
Common side effects include feeling tired, dizzy, or having a headache.
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About co-phenotrope
Tipo de medicamento | An antimotility medicine |
Usado para | Diarrea |
También llamado | Diphenoxylate hydrochloride with atropine sulfate |
Disponible como | Comprimidos |
Co-phenotrope is used in acute diarrhoea (this is diarrhoea which starts suddenly and lasts less than two weeks). It contains two ingredients: diphenoxylate hydrochloride and atropine sulfate. It is the diphenoxylate hydrochloride which is the main ingredient.
The most common cause of acute diarrhoea is infection. Other causes include drinking lots of beer, as a side-effect from other medicines, and anxiety. In most cases the diarrhoea settles within a few days, although it may take longer in some people. The main treatment is to have lots to drink to prevent lack of fluid in the body (dehydration). Antidiarrhoeal medicines like co-phenotrope may not be necessary; however, if you wish to reduce the number of trips that you need to make to the toilet, it can be useful. Most people only need to take it for a few days.
Diphenoxylate works by slowing down the activity of your bowel. This reduces the speed at which the contents pass through, and so food remains in your intestines for longer. This allows more water to be absorbed back into your body and results in firmer stools that are passed less often.
Because co-phenotrope regulates the passage of food through the digestive system, the tablets are also prescribed to help people regulate their bowel activity following surgery on the intestines.
Before taking co-phenotrope
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking co-phenotrope it is important that your doctor or pharmacist knows:
Si estás embarazada o amamantando.
Si tienes algún problema con el funcionamiento de tu hígado o el funcionamiento de tus riñones.
Si tienes algún problema respiratorio, como asma o enfermedad pulmonar obstructiva crónica (EPOC).
Si tienes problemas de próstata o alguna dificultad para orinar.
If you have been told you have low blood pressure.
Si tienes algún problema con tu tiroides o glándulas suprarrenales.
Si tienes epilepsia.
If you have a problem in your bile duct.
If you have a bowel obstruction or an inflammatory bowel problem.
Si tienes una condición que causa debilidad muscular, llamada miastenia gravis.
If you have ever had a drug addiction.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
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How to take co-phenotrope
Volver al contenidoBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about the tablets and a full list of the side-effects which you may experience from taking them.
Start by taking four tablets, and then take a further two tablets every six hours until the diarrhoea is controlled. Do not take more than 10 tablets in 24 hours.
Co-phenotrope should not be taken by a child under 16 years of age unless it is on the advice of a doctor. If your child has been prescribed co-phenotrope, check the label carefully to make sure you know what dose to give, as the dose will depend upon your child's age.
If you forget to take a dose, do not worry, just take a dose after the next time you pass some diarrhoea. Do not take two doses together to make up for a missed dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoIt is important that you have lots to drink to prevent you from becoming lacking in fluid in the body (dehydrated). Drinking plain water is ideal, but juice and/or soup are also suitable. Try to avoid drinks that contain a lot of sugar, such as cola or pop, as they can sometimes make diarrhoea worse.
Oral rehydration salts can be taken to help prevent dehydration and replace lost salts. These are especially recommended for children and for people who are frail or who have underlying health problems. You can buy these from a pharmacy.
Eat small, light meals as soon as you are able. Plain foods such as wholemeal bread and rice are good foods to try eating first.
If your symptoms continue for more than 48 hours, speak with a doctor or pharmacist for advice if you have not already done so.
If your symptoms get worse, or if you develop a high temperature, or if you pass blood in the diarrhoea, you should ask your doctor or pharmacist for advice as soon as possible.
If you buy any medicines check with a pharmacist that they are suitable to take with co-phenotrope. This is because the risk of side-effects can be increased when co-phenotrope tablets are taken with some other medicines.
Do not take more than the prescribed dose. If you suspect that someone has taken an overdose of this medicine, or that a child has taken it by accident, go to the accident and emergency department of your local hospital straightaway. Take the container with you, even if it is empty.
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Can co-phenotrope cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with co-phenotrope. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Co-phenotrope side-effects | ¿Qué puedo hacer si experimento esto? |
Sintiéndose cansado, somnoliento o mareado | Si esto ocurre, no conduzca y no use herramientas o máquinas hasta que se sienta mejor |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Tummy (abdominal) discomfort, feeling sick (nausea) | Try taking the tablets after eating some food if you are not already doing so |
Estreñimiento | Stop taking co-phenotrope |
Feeling confused or restless, mood changes, high temperature (fever), dry mouth, difficulty passing urine, feeling flushed | These should soon pass. If any become troublesome, stop taking co-phenotrope |
Si experimenta cualquier otro síntoma que crea que puede deberse al medicamento, hable con su médico o farmacéutico.
How to store co-phenotrope
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
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Preguntas frecuentes
Can co-phenotrope be used for chronic or long-term diarrhoea?
No, co-phenotrope is specifically used for acute diarrhoea, which starts suddenly and lasts less than two weeks. The article does not mention its use for chronic conditions.
What if I experience constipation while taking co-phenotrope?
If you experience constipation, you should stop taking co-phenotrope. This is listed as one of the side-effects of the medicine.
Are there any specific foods or drinks I should avoid while taking co-phenotrope for diarrhoea?
Yes, you should try to avoid drinks that contain a lot of sugar, such as cola or pop, as they can sometimes make diarrhoea worse. The article suggests plain water, juice, and/or soup for hydration.
How soon can I expect co-phenotrope to work in controlling my diarrhoea?
The article states that you should take two additional tablets every six hours until the diarrhoea is controlled. It implies that the medication should work within a short period to reduce the number of trips to the toilet.
My diarrhoea seems to be getting worse, or I have new symptoms like a high temperature or blood. What should I do?
If your symptoms get worse, or if you develop a high temperature, or if you pass blood in the diarrhoea, you should ask your doctor or pharmacist for advice as soon as possible.
Since co-phenotrope works by slowing bowel activity, can it be helpful for other digestive issues besides diarrhoea?
Yes, because co-phenotrope regulates the passage of food through the digestive system, it is also prescribed to help people regulate their bowel activity following surgery on the intestines.
Can I take other over-the-counter medicines while I'm using co-phenotrope?
If you buy any medicines, you should check with a pharmacist that they are suitable to take with co-phenotrope. This is important because the risk of side-effects can be increased when co-phenotrope tablets are taken with some other medicines.
Lecturas adicionales y referencias
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 26 de octubre de 2027
27 Abr 2023 | Última versión

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