Lactulosa para el estreñimiento
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 16 Oct 2023
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Lactulose can take up to 48 hours to have an effect.
If you find the medicine makes you feel queasy, mix your dose with some water or fruit juice. Alternatively, take your doses with a meal.
Eating a healthy diet, drinking plenty of water and getting regular gentle exercise can all help prevent constipation.
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About lactulose
Tipo de medicamento | An osmotic laxative |
Usado para | Estreñimiento |
Disponible como | Oral liquid medicine, liquid sachets |
Estreñimiento is a common problem. It can mean either going to the toilet less often than usual to empty your bowels, or passing hard or painful stools. Constipation can be caused by a number of things. Not eating enough fibre or not drinking enough fluid can cause constipation. Some conditions (such as pregnancy) can cause constipation, as can a lack of exercise or movement (such as being ill in bed) and some medicines.
Often, increasing the amount of fibre in your diet (such as by eating more fruit, vegetables, cereals, and wholemeal bread) and drinking plenty of water each day can effectively prevent or relieve constipation. You will have been recommended lactulose, a laxative, to help relieve constipation if you cannot increase the fibre in your diet or if this is insufficient. Lactulose works by drawing fluid into your bowel, which makes your stools softer and easier to pass. It is available on prescription, and it can also be bought without a prescription at pharmacies.
Lactulose also changes the acidity of the stools and this helps to discourage the growth of some germs (bacteria) present in the bowel. Because of this, lactulose is also prescribed for people with a liver disease called hepatic encephalopathy. If you have been prescribed it for this reason, ask your doctor if you need further information about the medicine.
Before taking lactulose
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lactulose it is important that your doctor or pharmacist knows:
Si estás tan estreñido que crees que puedes tener una obstrucción.
If you are unable to digest milk sugar (lactose intolerant).
If you have a condition called galactosaemia, where your body cannot process galactose.
If you are pregnant or breastfeeding. Lactulose is not known to be harmful to a baby, but while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
If it is intended for a child. This is because laxatives should only be given to children on the advice of a doctor or healthcare professional.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to this or to any other medicine.
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How to take lactulose
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from the pack. It will give you more information about lactulose and will provide you with a full list of the side-effects which you may experience.
Take lactulose exactly as your doctor tells you to, or as directed on the pack. The usual dose for constipation in an adult is 15 ml (three 5 ml spoonfuls) twice daily, although the dose you are advised to take may be different from this as it will be adjusted to suit your needs.
If a doctor or healthcare professional has recommended lactulose for your child, check the label on the pack carefully to make sure that you give the correct dose for the age of your child.
Si olvida tomar una dosis, no se preocupe, simplemente tome la siguiente dosis cuando corresponda. No tome dos dosis juntas para compensar una dosis olvidada.
Obteniendo el máximo de tu tratamiento
Volver al contenidoLactulose can take up to 48 hours to act, so it may take two or three days before you feel the full benefit. However, if after several days you do not feel your symptoms are improving, or if they get worse, you should speak with a doctor for further medical advice.
It is important for you to drink plenty while you are constipated. Adults should aim to drink at least two litres (about 8-10 cups) of fluid per day. Most sorts of drink will do, but as a start, try just drinking a glass of water 3-4 times a day in addition to what you normally drink.
Intenta comer una dieta equilibrada que contenga alimentos ricos en fibra, como panes y cereales integrales, frutas y verduras, arroz integral y pasta integral. Si no estás acostumbrado a una dieta alta en fibra, puede ser mejor aumentar la cantidad de fibra que consumes gradualmente.
Mantener tu cuerpo activo te ayudará a mantener en movimiento tu sistema digestivo, así que intenta hacer ejercicio diario de forma regular.
You may wish to include some foods in your diet that contain sorbitol. Sorbitol is a naturally occurring sugar. It is not digested very well and draws water into your bowel which has an effect of softening stools. Fruits (and their juices) that have a high sorbitol content include apples, apricots, gooseberries, grapes (and raisins), peaches, pears, plums, prunes, raspberries and strawberries.
You can read more about how to prevent or treat constipation in the separate health information leaflets called Estreñimiento (for adults) and Estreñimiento en Niños.
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Can lactulose cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones which can occur with lactulose. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Lactulose side-effects | ¿Qué puedo hacer si experimento esto? |
Excess wind (flatulence), tummy (abdominal) discomfort or cramps | These effects soon settle down as your body adjusts but if they continue or become troublesome, speak with your doctor or pharmacist for further advice |
Sentirse mal (náuseas) o estar enfermo (vómitos) | Try taking lactulose with meals, or mixing your dose with some water or fruit juice |
Si experimenta otros síntomas que cree que pueden deberse al medicamento, hable con su médico o farmacéutico para obtener más consejos.
How to store lactulose
Volver al contenidoMantenga todos los medicamentos fuera de la vista y del alcance de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Si compras algún medicamento, consulta con un farmacéutico que sea seguro tomarlo junto con tus otros medicamentos.
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy who will dispose of them for you.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Duphalac 3.335 g/5 ml Oral Solution; Mylan Products Ltd, The electronic Medicines Compendium. Dated April 2022.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 15 Oct 2026
16 Oct 2023 | Última versión

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