Lercanidipine tablets for high blood pressure
Zanidip
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 31 Mar 2025
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Take lercanidipine once a day, preferably in the morning. You should take the tablet about 30 minutes before you eat.
Do not drink grapefruit juice whilst you are on lercanidipine. It can interact with the medicine and alter its effect.
When you first start lercanidipine you may get headache, feel flushed, or feel dizzy. These effects are usually mild and only last for a few days.
Sf you have any chest pain after taking this medicine, contact your doctor for advice straightaway.
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About lercanidipine
Tipo de medicamento | Un bloqueador de los canales de calcio |
Usado para | Presión arterial alta |
También llamado | Zanidip® |
Disponible como | Comprimidos |
Lercanidipine is prescribed to treat presión arterial alta (hipertensión). Although people with high blood pressure often do not feel unwell, if left untreated, high blood pressure can harm the heart and damage blood vessels, and could lead to a heart attack or stroke.
Lercanidipine is known as a calcium-channel blocker because it works by affecting the way calcium passes into certain muscle cells in your blood vessels. The muscle cells need calcium to contract. Lercanidipine reduces the amount of calcium that goes into these muscle cells. This causes the muscle cells to relax, which widens your blood vessels and lowers your blood pressure.
Before taking lercanidipine
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lercanidipine it is important that your doctor knows:
Si estás embarazada o amamantando.
Si tienes algún problema con el funcionamiento de tu hígado, o algún problema con el funcionamiento de tus riñones.
If you have a heart condition, or angina chest pain, or if you have recently had a heart attack.
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take lercanidipine
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about lercanidipine, and will also provide you with a full list of the side-effects which you could experience from taking it.
Lercanidipine is available in two strengths of tablet - 10 mg and 20 mg. The usual starting dose is 10 mg daily. If it becomes necessary, your doctor will increase your dose after a few weeks to 20 mg daily. Take the tablets exactly as your doctor tells you to.
It is likely that you will be advised to take your dose in the morning before breakfast. Try to take your doses at the same time each day. Having a routine will help you to remember to take your doses regularly.
Swallow the tablet with a drink of water. You should take lercanidipine when your stomach is empty, so about 30 minutes before a meal. This is because fatty food can increase the amount of lercanidipine your body absorbs, which could then lead to you experiencing side-effects.
If you forget to take a dose at your usual time, take it 30 minutes before your next meal. If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoIntenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
Do not drink grapefruit juice while you are on lercanidipine. This is because a substance in grapefruit juice increases the amount of lercanidipine in your bloodstream and this increases the risk of side-effects.
If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on lercanidipine as the chance of side-effects (such as feeling dizzy and light-headed) is increased.
If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside your prescribed medicines. This is because a number of medicines can interfere with lercanidipine and so may not be recommended for you.
If you are due to have an operation or any dental treatment, tell the person carrying out the treatment that you are taking lercanidipine tablets. Lercanidipine and some anaesthetics can interact, meaning that unwanted effects can be more likely.
Treatment with lercanidipine is usually long-term. Continue to take the tablets unless you are advised otherwise by your doctor. If it becomes necessary for you to stop treatment, your doctor may want you to reduce your dose gradually over a few days, as stopping taking lercanidipine suddenly can cause problems.
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Can lercanidipine cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with lercanidipine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Lercanidipine side-effects (these affect fewer than 1 in 100 people) | ¿Qué puedo hacer si experimento esto? |
Dolor de cabeza | This usually soon passes, but you can ask your pharmacist to recommend a suitable painkiller in the meantime |
Sensación de mareo | Si esto ocurre, no conduzca y no use herramientas o máquinas hasta que se sienta mejor |
Swollen ankles, feeling flushed, being aware of your heartbeat, a fast heartbeat | Speak with your doctor about these if any become troublesome or continue beyond a few days |
Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.
How to store lercanidipine
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda de inmediato al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
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Informe los efectos secundarios sospechosos de medicamentos, vacunas, cigarrillos electrónicos, incidentes con dispositivos médicos, productos defectuosos o falsificados (falsos) a la Agencia Reguladora de Medicamentos y Productos Sanitarios para garantizar un uso seguro y efectivo.

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Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Zanidip® 10 mg and 20 mg tablets; Recordati Pharmaceuticals Limited, The electronic Medicines Compendium. Dated April 2021.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 8 May 2025
31 Mar 2025 | Última versión

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