Can I take Venlafaxine and Sildenafil together?

Por qué sucede esto

Sildenafil works by widening blood vessels to increase blood flow, which can lower blood pressure. Venlafaxine can also cause changes in blood pressure (usually an increase, but sometimes a drop when standing up). When used together, these effects can lead to an unpredictable drop in blood pressure. Furthermore, venlafaxine is an antidepressant that can cause sexual dysfunction, potentially counteracting the desired effects of sildenafil.

You should use this combination with caution. When starting sildenafil or increasing your dose, be mindful of how you feel when standing up from a sitting or lying position. If you feel dizzy or faint, sit or lie down immediately. It is best to avoid or strictly limit alcohol, as it can worsen these side effects. If you find that sildenafil is not working well for you, or if you experience severe dizziness, speak to your doctor.

Trastornos de depresión y ansiedad

La venlafaxina puede causar un aumento en los pensamientos suicidas o autolesiones, especialmente al comenzar el tratamiento o al cambiar la dosis. Vigile su estado de ánimo de cerca y busque ayuda médica urgente si nota cambios preocupantes.

Uso de medicamentos con nitratos

NEVER take sildenafil if you use nitrate medicines for chest pain (e.g. glyceryl trinitrate, isosorbide mononitrate) or 'poppers'. Combining them causes a dangerous, potentially fatal drop in blood pressure.

Trastornos de la coagulación

La venlafaxina puede aumentar su riesgo de sangrado, especialmente si también está tomando aspirina, AINEs (como ibuprofeno) o medicamentos anticoagulantes como warfarina. Consulte a un médico si nota moretones o sangrado inusuales.

Sudden vision loss or priapism

Seek immediate medical help if you experience a sudden decrease or loss of vision, or if you have an erection that lasts for more than 4 hours.

Síndrome de serotonina

Combinar venlafaxina con otros medicamentos que afectan la serotonina (como la hierba de San Juan o ciertos analgésicos) puede causar una condición potencialmente mortal llamada síndrome de serotonina. Los síntomas incluyen agitación, alucinaciones, ritmo cardíaco acelerado y rigidez muscular.

Alcohol

It is best to avoid or strictly limit alcohol while taking venlafaxine. Combining alcohol with this medicine can increase drowsiness, dizziness, and the risk of coordination problems. It may also worsen the symptoms of your underlying condition.

It is best to avoid or strictly limit alcohol when taking sildenafil. Alcohol can make it more difficult to get an erection and can also increase the risk of side effects such as dizziness and low blood pressure.

Jugo de toronja

Grapefruit juice can increase the amount of sildenafil in your bloodstream. This makes side effects like headaches, flushing, or low blood pressure more likely. It is best to avoid drinking large amounts of grapefruit juice while using this medicine.

Comidas ricas en grasa

If you take sildenafil with a heavy or high-fat meal (such as a burger or chips), the medicine may take longer to start working.

Cafeína

La venlafaxina puede aumentar ocasionalmente su presión arterial o ritmo cardíaco. Consumir grandes cantidades de cafeína (que se encuentra en el café, té y bebidas energéticas) puede empeorar estos efectos o aumentar los sentimientos de ansiedad e inquietud.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.