Can I take Alogliptin and Bisoprolol together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
- Add to preferred sources on Google
Taking bisoprolol with alogliptin may occasionally hide the warning signs of low blood sugar (hypoglycaemia). It can also slightly increase the risk of your blood sugar dropping too low.
Why this happens
Bisoprolol is a beta-blocker. These medicines can mask the physical symptoms of low blood sugar, such as a fast heartbeat or tremors. Additionally, beta-blockers can sometimes interfere with how the body releases glucose, which may enhance the blood-sugar-lowering effect of alogliptin.
What you should do
You can take these medicines together, but you should be aware that you might not feel the usual 'shaky' or 'racing heart' sensations if your blood sugar drops. Pay closer attention to other signs of low blood sugar, such as sweating, hunger, or blurred vision. Monitor your blood glucose levels regularly as advised by your doctor.
Important precautions
Asthma or Chronic Obstructive Pulmonary Disease (COPD)
Bisoprolol can cause narrowing of the airways, which may trigger a severe asthma attack or worsen breathing difficulties. Ensure your doctor knows if you have a history of wheezing.]
Acute Pancreatitis
Stop taking alogliptin and seek immediate medical help if you experience severe and persistent stomach pain, which may reach through to your back, as this can be a sign of an inflamed pancreas.
Food and drink warnings
Alcohol
Drinking alcohol can increase the blood-pressure-lowering effect of bisoprolol, which may make you feel dizzy or light-headed, especially when you first start taking it or if your dose is increased. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Flecainide and Wegovy together?
Wegovy (semaglutide) can slow down how quickly your stomach empties. This might change how your body absorbs flecainide, which is a medicine that needs to be kept at very specific levels in your blood to work safely and effectively. Additionally, both medications can occasionally affect your heart rhythm or heart rate.

Drug interactions checker
Can I take Mounjaro and Insulin together?
Taking Mounjaro (tirzepatide) and insulin together significantly increases your risk of having a 'hypo' (hypoglycaemia), which is when your blood sugar levels drop too low. Symptoms of a hypo can include feeling shaky, sweaty, dizzy, hungry, or confused. In severe cases, it can be dangerous.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.
More in drug interactions checker
- Can I take Amitriptyline and Colecalciferol together?
- Can I take Amlodipine and Paracetamol together?
- Can I take Aspirin and Doxazosin together?
- Can I take Atorvastatin and Biotin together?
- Can I take Atorvastatin and Furosemide together?
- Can I take Black garlic and Evening primrose oil together?
- Can I take Chaga and Lions mane together?
- Can I take Co-codamol and Sukkarto together?
- Can I take Danazol and Sertraline together?
- Can I take Doxadura and Losartan together?
- Can I take Fluanxol and Vitamin D together?
- Can I take Indapamide and Ramipril together?
- Can I take Losartan and Trazodone together?
- Can I take Methotrexate and Ibuprofen together?
- Can I take Omeprazole and Paracetamol together?
- Can I take Omeprazole and Sertraline together?
- Can I take Omeprazole and Simvastatin together?
- Can I take Sertraline and Paracetamol together?
- Can I take Solifenacin and Vitamin B12 together?
- Can I take Vitamin B12 and Vitamin C together?