Can I take Ashwagandha and Vitamin b12 together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known clinical interactions between ashwagandha and vitamin B12. It is generally considered safe to take these two supplements together.
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Why this happens
Ashwagandha (Withania somnifera) and Vitamin B12 (cobalamin) use different pathways in the body. Ashwagandha is primarily metabolised by liver enzymes, while Vitamin B12 is absorbed in the small intestine and stored in the liver. They do not compete for absorption or interfere with each other's effects.
What you should do
You can continue to take both supplements as directed. However, always inform your doctor or pharmacist about all supplements you are taking, especially if you have an underlying thyroid condition or are scheduled for surgery, as ashwagandha can affect thyroid hormone levels and may have a mild sedative effect.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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