Can I take Esomeprazole and Vitamin B12 together?
Guía de interacción de medicamentos
Publicado originalmente 25 Ene 2026
Cumple con las directrices editoriales
- DescargarDescargar
- Compartir
- Language
- Discusión
- Versión en audio
- Add to preferred sources on Google
Taking esomeprazole for a long time can make it harder for your body to absorb vitamin B12 from your food. Over several years, this could lead to a vitamin B12 deficiency.
En este artículo:
Video picks for Interacciones de medicamentos
Continúa leyendo abajo
Por qué sucede esto
Vitamin B12 needs stomach acid to be released from the proteins in your food so it can be absorbed. Esomeprazole works by reducing the amount of acid your stomach produces. Less acid means less vitamin B12 is released and absorbed into your system.
Lo que deberías hacer
Volver al contenidoIf you take esomeprazole long-term (more than 2 or 3 years), talk to your doctor about your vitamin B12 levels. They may suggest a simple blood test or a supplement. If you already take B12 supplements or injections, this interaction is less of a concern as these forms are usually absorbed more easily.
Continúa leyendo abajo
Precauciones importantes
Volver al contenidoDiarrea severa
Esomeprazole can increase your risk of developing a serious bowel infection caused by Clostridium difficile. If you develop severe, watery, or persistent diarrhoea, seek medical advice immediately.
Lupus (SCLE)
Esomeprazole can rarely cause a specific skin reaction called Subacute Cutaneous Lupus Erythematosus. If you develop a skin rash, especially in areas exposed to the sun, or joint pain, you must inform your doctor as you may need to stop the treatment.
Deficiencia de vitamina B12 y fracturas óseas - esomeprazol
El uso a largo plazo (más de un año) puede debilitar los huesos y llevar a niveles bajos de magnesio o B12; su médico debería monitorear estos si está en tratamiento a largo plazo.
Enfermedad grave de riñón o hígado
Es posible que su médico necesite recetarle una dosis más baja, ya que su cuerpo tardará más en eliminar el esomeprazol.
Deficiencia de magnesio
Tomarsomeprazole for more than three months can cause your blood magnesium levels to drop significantly, leading to fatigue, muscle spasms, or dizziness.
Enmascarando los síntomas del cáncer de estómago
El esomeprazol puede ocultar los síntomas del cáncer de estómago. Debe informar a su médico si tiene pérdida de peso inexplicada, vómitos persistentes o dificultad para tragar antes de comenzar este medicamento.
Advertencias sobre alimentos y bebidas
Volver al contenidoAlcohol
While alcohol does not directly interact with esomeprazole, it can increase stomach acid production and irritate the stomach lining, which may worsen the symptoms you are taking esomeprazole to treat. It is best to limit or avoid alcohol if you have acid-related issues.
It is best to avoid or strictly limit alcohol while taking Vitamin B12. Heavy alcohol consumption can interfere with the body's ability to absorb Vitamin B12 from the gut and can reduce the amount of the vitamin stored in the liver.
Cafeína (Café, Té, Bebidas Energéticas)
Caffeine can trigger or worsen symptoms of acid reflux and heartburn. If you are taking esomeprazole for these conditions, you may find that reducing caffeine intake helps the medicine work more effectively.
Continúa leyendo abajo
Uso de otros medicamentos
Volver al contenidoTaking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.
Patient picks for Interacciones de medicamentos

Verificador de interacciones de medicamentos
Can I take Lisinopril and Potassium together?
Taking lisinopril and potassium supplements together can cause the levels of potassium in your blood to become dangerously high (a condition called hyperkalaemia). While your body needs potassium for your heart and muscles to work, too much of it can lead to serious heart rhythm problems or even cause the heart to stop. Symptoms of high potassium can include muscle weakness, tingling sensations, or palpitations, but often there are no symptoms until the level is very high.

Verificador de interacciones de medicamentos
Can I take Aspirin and Furosemide together?
Taking aspirin and furosemide together can make the furosemide (water tablet) less effective at removing excess fluid from your body. Additionally, at high doses of aspirin, there is an increased risk of kidney problems and a build-up of aspirin in your blood, which can lead to side effects like ringing in the ears (tinnitus).
Continúa leyendo abajo
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
25 Ene 2026 | Publicado originalmente

Pregunta, comparte, conecta.
Navega por discusiones, haz preguntas y comparte experiencias en cientos de temas de salud.

¿Te sientes mal?
Evalúa tus síntomas en línea de forma gratuita
Suscríbete al boletín de Patient
Tu dosis semanal de consejos de salud claros y confiables, escritos para ayudarte a sentirte informado, seguro y en control.
By subscribing you accept our Política de Privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.