Can I take Anastrozole and Levothyroxine together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between anastrozole and levothyroxine. Taking these two medicines together is generally considered safe and should not change how well either drug works.
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Why this happens
Anastrozole (used for breast cancer) and levothyroxine (used for an underactive thyroid) are processed by different pathways in the body. They do not interfere with each other's absorption, metabolism, or excretion, nor do they have opposing or overlapping effects on the body's systems.
What you should do
You can continue to take both medications as prescribed by your doctor. It is usually best to take levothyroxine on an empty stomach, first thing in the morning, at least 30 to 60 minutes before breakfast or taking other medications like anastrozole, to ensure it is absorbed properly. Always inform your doctor if you notice any new symptoms or changes in your health.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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