Can I take Amlodipine and Losartan together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking amlodipine and losartan together can cause your blood pressure to drop lower than if you took either medicine alone. While this is often the intended goal of your treatment, it can sometimes lead to side effects like dizziness, lightheadedness, or fainting, especially when you stand up quickly. There is also a small risk of affecting your kidney function or increasing potassium levels in your blood.
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Why this happens
Both medicines work to lower blood pressure but in different ways: amlodipine relaxes the muscles in your blood vessel walls, while losartan blocks a hormone that causes blood vessels to tighten. Using them together has an 'additive' effect, meaning their combined power is stronger.
What you should do
This is a very common and effective combination prescribed by doctors. You should continue taking your medication as directed, but be mindful of feeling dizzy or faint. To prevent this, try to stand up slowly from a sitting or lying position. Your doctor may want to perform routine blood tests to check your kidney function and potassium levels. If you feel severely dizzy or have a fainting spell, contact your GP.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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