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Can I take Amlodipine and Losartan together?

Guía de interacción de medicamentos

Taking amlodipine and losartan together can cause your blood pressure to drop lower than if you took either medicine alone. While this is often the intended goal of your treatment, it can sometimes lead to side effects like dizziness, lightheadedness, or fainting, especially when you stand up quickly. There is also a small risk of affecting your kidney function or increasing potassium levels in your blood.

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Puedes tomar amlodipina y losartán together but be mindful of feeling dizzy or faint. They are commonly prescribed together to lower blood pressure.

To avoid feeling dizzy or faint, try to stand up slowly from a sitting or lying position.

Your doctor may want to perform routine blood tests to check your kidney function and potassium levels.

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Por qué sucede esto

Both medicines work to lower blood pressure but in different ways: amlodipine relaxes the muscles in your blood vessel walls, while losartan blocks a hormone that causes blood vessels to tighten. Using them together has an 'additive' effect, meaning their combined power is stronger.

You may be experiencing an interaction between amlodipine and losartan if:

  • You feel dizzy or lightheaded, especially when standing up.

  • You experience fainting or near-fainting episodes.

  • You notice swelling of the ankles or feet.

  • You develop headaches or flushing.

  • You feel unusually tired or weak.

  • Blood tests show changes in kidney function or potassium levels.

  • Symptoms start after starting or increasing the dose of either medicine.

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Si tienes alguno de los síntomas mencionados, deberías:

  • Speak to your GP or pharmacist for advice as soon as possible.

  • Do not stop taking amlodipine or losartan suddenly unless advised by a healthcare professional.

  • Seek urgent medical help if you faint or feel severely unwell.

  • Attend any blood pressure checks or blood tests arranged to monitor kidney function and potassium levels.

  • Informe a su profesional de la salud sobre todos los demás medicamentos y suplementos que está tomando.

Embarazo

You must not take losartan if you are pregnant or planning to become pregnant. It can cause serious harm or death to an unborn baby, particularly if used in the second and third trimesters.

High potassium levels (hyperkalaemia)

Losartan can increase potassium levels in your blood. Avoid using salt substitutes containing potassium and be cautious with potassium supplements, as high levels can affect your heart rhythm.

Grapefruit

Avoid eating grapefruit or drinking grapefruit juice while taking amlodipine. Grapefruit can significantly increase the amount of amlodipine in your blood, making side effects like dizziness and headaches much more likely.

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Alcohol

Alcohol can increase the blood pressure-lowering effect of these medicines, which may make you feel dizzy, lightheaded, or faint, especially when standing up.

It is best to keep alcohol intake within recommended limits and see how the medicine affects you first.

Salt substitutes (potassium-based)

Losartan can increase the levels of potassium in your blood. Using salt substitutes that contain potassium (such as Lo-Salt) can lead to dangerously high potassium levels (hyperkalaemia).

Check with your pharmacist before using these.

¿Tomas múltiples medicamentos? Nuestro Verificador de Interacciones de Medicamentos te ayuda a verificar si tus recetas, medicamentos de venta libre y suplementos son seguros para tomar juntos. Simplemente busca tus medicamentos para ver posibles interacciones y qué hacer al respecto.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 25 Ene 2026 | Publicado originalmente
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