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Can I take St john's wort and Vitamin b2 together?

Drug interaction guide

There is no known harmful interaction between St John's Wort and Vitamin B2 (riboflavin). Taking them together is generally considered safe.

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Why this happens

St John's Wort is known for affecting how the liver processes many medicines (via the CYP450 enzyme system), but Vitamin B2 is a water-soluble vitamin that is not processed in a way that interferes with this herbal supplement. They do not compete for the same pathways in the body.

What you should do

You can take these two together. However, always inform your doctor or pharmacist about all supplements you are taking, as St John's Wort can interact with many prescription medications, such as blood thinners, birth control, and antidepressants.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • 25 Enero 2026 | Publicado originalmente
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