Can I take Magnesium and Simvastatin together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking magnesium supplements at the same time as simvastatin can lower the amount of the medicine your body absorbs. This means the simvastatin may not work as well to lower your cholesterol.
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Why this happens
Magnesium (often found in antacids or supplements) can bind to simvastatin in the digestive tract or change the acidity of the stomach, which reduces the amount of the drug that enters your bloodstream.
What you should do
You do not need to stop taking either, but you should separate the doses. Take your simvastatin at least 2 hours before or 2 hours after taking any magnesium supplement or magnesium-containing antacid.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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