Can I take Atorvastatin and Sertraline together?

You can usually take atorvastatina y sertralina together, but with caution.

Combining them may slightly increase the levels of atorvastatin in your blood, increasing the risk of side effects such as muscle pain or weakness.

Por qué sucede esto

Both medications are processed by the same enzymes in the liver (specifically CYP3A4). Because they are 'competing' for the same processing pathway, the body may break down atorvastatin more slowly than usual.

• Tell your doctor if you experience any unexplained muscle pain, tenderness, or weakness, especially if you also feel generally unwell or have a fever.

• Your doctor may monitor your liver function or muscle enzymes (CK levels) via blood tests.

• Do not take atorvastatin if you are pregnant.

Trastornos de depresión y ansiedad

Es posible que experimente un aumento en los pensamientos suicidas o el impulso de autolesionarse al comenzar a tomar sertralina o al cambiar la dosis. Esto es más frecuente en adultos jóvenes menores de 25 años. Comuníquese con su médico o acuda a un hospital de inmediato si nota cambios en su estado de ánimo o comportamiento.

Síndrome de serotonina

Taking these medicines together significantly increases the risk of serotonin syndrome, a potentially life-threatening condition. Seek urgent medical help if you experience high fever, agitation, confusion, or muscle twitching.

Embarazo

No debe tomar atorvastatina si está embarazada o planea quedar embarazada, ya que puede causar daños graves a un bebé no nacido. Utilice anticonceptivos efectivos mientras toma este medicamento.

Muscle disorders - atorvastatin

Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.

Riesgo de sangrado

Sertraline increases your risk of bleeding. Seek medical advice before taking anti-inflammatory painkillers such as ibuprofen or aspirin, as the combination can cause serious stomach bleeding.

Alcohol

While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver problems and muscle side effects.

It is best to avoid or strictly limit alcohol while taking sertraline. Combining alcohol with this medicine can increase side effects like drowsiness, dizziness, and impaired coordination. Additionally, both alcohol and sertraline can affect your mood, potentially making symptoms of depression or anxiety worse.

Jugo de toronja

You should avoid drinking large amounts of grapefruit juice while taking sertraline. Grapefruit contains compounds that can increase the levels of sertraline in your blood, which may increase the risk of experiencing side effects.

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage.

Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Cafeína (Café, Té, Bebidas Energéticas)

La sertralina puede causar nerviosismo o temblores en ocasiones. Consumir grandes cantidades de cafeína puede empeorar estos efectos secundarios o aumentar los sentimientos de ansiedad. Se recomienda controlar su ingesta de cafeína.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.