Can I take Levothyroxine 25 and Vitamin d3 together?
Drug interaction guide
Originally published 25 Jan 2026
Satisface las necesidades del paciente directrices editoriales
- DescargarDescargar
- Compartir
- Idioma
- Debate
There is no direct harmful interaction between levothyroxine and vitamin D3. In fact, many people take them together because vitamin D deficiency is common in people with thyroid conditions. However, the timing of when you take them is important to ensure your thyroid medication works properly.
En este artículo:
Seguir leyendo
Why this happens
While vitamin D itself doesn't interfere with levothyroxine, many vitamin D supplements also contain calcium. Calcium is known to bind to levothyroxine in the stomach, which prevents the thyroid medicine from being absorbed into your bloodstream. Even if your supplement only contains vitamin D, taking it at the same time as your thyroid pill can sometimes interfere with the very specific conditions needed for levothyroxine to be absorbed.
What you should do
You should take your levothyroxine on an empty stomach, at least 30 to 60 minutes before breakfast. To be safe, wait at least 4 hours after taking your levothyroxine before taking your vitamin D3 supplement. This ensures your body gets the full dose of your thyroid medication.
Seguir leyendo
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Tratamiento y medicación
Can I take Esomeprazole and Trazodone together?
Esomeprazole may reduce the amount of trazodone that your body absorbs. This could potentially make trazodone less effective at treating your symptoms (such as depression or sleep issues). Additionally, both medications can rarely affect the electrical activity of your heart, though this risk is generally low.

Tratamiento y medicación
Can I take Magnesium and Bisoprolol together?
Taking magnesium and bisoprolol together can lead to an excessively slow heart rate or a significant drop in blood pressure. This may cause you to feel dizzy, lightheaded, or faint.
Seguir leyendo
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

Pregunte, comparta, conecte.
Explore debates, formule preguntas y comparta experiencias sobre cientos de temas de salud.

¿Se encuentra mal?
Evalúe sus síntomas en línea de forma gratuita
Suscríbase al boletín informativo para pacientes.
Tu dosis semanal de consejos de salud claros y fiables, redactados para ayudarte a sentirte informado, seguro y en control.
Al suscribirte, aceptas nuestra Política de privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.