Can I take Amlodopine and Atorvastatin together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together can increase the amount of atorvastatin in your blood. This may increase the risk of side effects, particularly muscle pain, tenderness, or weakness (a condition called myopathy). In very rare cases, this can lead to a serious kidney problem called rhabdomyolysis.
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Why this happens
Amlodipine can slow down the process by which your liver breaks down atorvastatin. Because the liver is busy processing the amlodipine, the atorvastatin stays in your system longer and reaches higher levels than intended.
What you should do
It is common for these drugs to be prescribed together, but your doctor may choose to limit your dose of atorvastatin (usually to no more than 20mg or 40mg daily) to keep you safe. If you experience any unexplained muscle pain, tenderness, or weakness—especially if you also have a fever or feel generally unwell—contact your doctor immediately.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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