Can I take Atorvastatin and Levothyroxine together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together is generally safe, but there is a minor interaction where atorvastatin might slightly increase the levels of levothyroxine in your blood. Conversely, your thyroid levels can affect how well atorvastatin works to lower your cholesterol.
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Why this happens
Atorvastatin may slightly interfere with the proteins that carry thyroid hormone in your blood, potentially increasing the amount of active levothyroxine. Additionally, if your thyroid condition is not well-controlled (hypothyroidism), it can naturally raise your cholesterol levels, making the statin appear less effective.
What you should do
You can take these medicines together. However, you should have your thyroid function (TSH levels) monitored regularly by your doctor, especially when starting or changing the dose of atorvastatin. If you notice symptoms of an overactive thyroid, such as a racing heart, feeling unusually hot, or tremors, inform your GP.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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