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Can I take Accrete d3 and Furosemide together?

Drug interaction guide

Taking Accrete D3 (calcium and vitamin D3) with furosemide can lead to a build-up of calcium in your blood, a condition called hypercalcaemia. It can also make your furosemide less effective at removing excess fluid from your body.

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Why this happens

Furosemide is a 'water pill' that usually helps the kidneys get rid of calcium. However, vitamin D (in Accrete D3) increases how much calcium your body absorbs. If the balance is off, calcium levels can rise too high. Additionally, high calcium levels can sometimes interfere with how well furosemide works to reduce swelling or lower blood pressure.

You should speak to your doctor before taking these together. They may want to monitor your blood calcium levels and kidney function regularly. If you experience symptoms of high calcium—such as feeling very thirsty, needing to urinate more often, nausea, constipation, or unusual tiredness—contact your GP.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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