Can I take Cordyceps and Lions mane together?
Drug interaction guide
Originally published 24 Jan 2026
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There are no known negative interactions between Cordyceps and Lion's Mane mushrooms. In fact, they are frequently taken together in 'mushroom blends' because they work in different ways—Cordyceps is typically used for energy and physical stamina, while Lion's Mane is used for brain health and focus. Taking them together may provide a combined benefit for both physical and mental performance.
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Why this happens
These two supplements do not compete for the same metabolic pathways in the liver, nor do they cancel each other out. They have 'additive' effects, meaning they work alongside each other without interfering with how the body absorbs or uses them.
What you should do
It is generally safe to take these together. However, as with any supplement, start with a low dose to see how your body reacts. If you are taking blood-thinning medication or have an upcoming surgery, speak to your doctor first, as both mushrooms may have very mild blood-thinning properties.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
24 Enero 2026 | Publicado originalmente
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