Can I take Atorvastatin and Reishi together?
Drug interaction guide
Originally published 24 Jan 2026
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Taking reishi mushroom with atorvastatin may increase the risk of liver strain or muscle-related side effects. Reishi may also have a mild blood-thinning effect, which could be relevant if you take other medications.
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Why this happens
Both atorvastatin and reishi are processed by the liver. Reishi may interfere with the enzymes (specifically CYP3A4) that break down atorvastatin, potentially leading to higher levels of the medication in your bloodstream. Additionally, both substances can affect liver function markers.
What you should do
Consult your doctor before combining these two. If you decide to take them together, watch for signs of liver issues (such as yellowing of the eyes/skin or dark urine) or unusual muscle pain, tenderness, or weakness. Your doctor may want to monitor your liver function more closely.
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Using other medicines?
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
24 Enero 2026 | Publicado originalmente
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