Can I take Oxypro and Ripinrole together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together can make you feel very sleepy, dizzy, or lightheaded. It may also increase the risk of 'sleep attacks' (suddenly falling asleep during the day) and can cause breathing to become slow or shallow.
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Why this happens
Both medicines affect the central nervous system. Oxypro (oxycodone) is a strong painkiller that slows down brain activity, and ropinirole (used for Parkinson's or Restless Legs Syndrome) can also cause significant drowsiness. When used together, these effects add up, making the sedative impact much stronger.
What you should do
You should speak to your doctor before taking these together. If your doctor confirms you need both, start with the lowest possible doses. Do not drive or operate machinery until you know how this combination affects you. Seek medical help immediately if you experience extreme sleepiness, confusion, or difficulty breathing.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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