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Can I take Lansoprazole and Magnesium together?

Guía de interacción de medicamentos

Taking lansoprazole and magnesium supplements together can lead to two main issues. First, the magnesium may interfere with how well the body absorbs lansoprazole, making it less effective at treating acid reflux or ulcers. Second, if you take lansoprazole for a long time (usually more than three months), it can actually cause your body's magnesium levels to drop too low, which can lead to tiredness, muscle cramps, or irregular heartbeats.

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Por qué sucede esto

Magnesium supplements (especially antacids) can coat the stomach or change its acidity, which prevents lansoprazole from being absorbed properly into the bloodstream. Conversely, long-term use of proton pump inhibitors like lansoprazole can interfere with the way the intestines absorb magnesium from food and supplements, leading to a deficiency.

To ensure your medicine works properly, leave a gap of at least 2 hours between taking your lansoprazole and your magnesium supplement. If you are taking lansoprazole for a long period, your doctor may want to perform occasional blood tests to check your magnesium levels. Contact your doctor if you experience muscle tremors, spasms, or a very fast heartbeat.

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Diarrea severa

Lansoprazole can increase your risk of developing a serious bowel infection caused by C. difficile. If you develop severe, watery, or persistent diarrhoea, seek medical advice immediately and do not use anti-diarrhoeal medicines.

Enfermedad renal

If you have kidney problems, you must not take magnesium supplements without medical supervision, as your kidneys may not be able to remove excess magnesium from your blood, leading to toxic levels.

Low magnesium levels (Hypomagnesaemia)

Taking lansoprazole for more than three months can cause your blood magnesium levels to drop dangerously low. This is especially critical if you are already taking magnesium supplements or medicines like digoxin.

Productos lácteos (Leche, Queso, Yogur)

Dairy products are high in calcium. Calcium can compete with magnesium for absorption in the gut. It is best to take your magnesium supplement at least 2 hours apart from eating large amounts of dairy.

Alimentos (General)

Lansoprazole works best when taken on an empty stomach, at least 30 minutes before a meal. Taking it with food can slow down how quickly the medicine is absorbed and make it less effective.

Caffeine (Coffee, Tea, Energy drinks)

While there is no direct chemical interaction, caffeine can increase stomach acid production and relax the oesophageal sphincter. This may worsen the symptoms (like heartburn) that lansoprazole is intended to treat.

Alcohol

Alcohol does not stop lansoprazole from working, but it can irritate the stomach lining and increase acid production, which may make your symptoms worse.

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Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 14 Mar 2026 | Publicado originalmente
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