Can I take Amlodopine and Sertraline together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking amlodipine and sertraline together may increase the risk of your blood pressure dropping too low. It can also occasionally lead to a rare but serious heart rhythm problem.
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Why this happens
Both medications can affect the electrical activity of the heart. Additionally, sertraline may slightly interfere with how the liver breaks down amlodipine, potentially leading to higher levels of the blood pressure medicine in your system.
What you should do
You can usually take these together, but you should monitor your blood pressure regularly. Seek medical advice if you feel dizzy, lightheaded, faint, or notice a fluttering sensation in your chest (palpitations). Your doctor may want to check your heart rhythm (ECG) if you are on high doses.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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