Can I take Losartan and Sertraline together?
Drug interaction guide
Originally published 25 Jan 2026
Satisface las necesidades del paciente directrices editoriales
- DescargarDescargar
- Compartir
- Idioma
- Debate
Taking these two medicines together can sometimes cause your blood pressure to drop lower than intended. This might make you feel dizzy, lightheaded, or faint, especially when you stand up quickly. There is also a small risk that the combination could affect the levels of sodium (salt) in your blood.
En este artículo:
Seguir leyendo
Why this happens
Both medicines can independently lower blood pressure. Losartan is designed to do this, while sertraline can sometimes cause low blood pressure as a side effect. Additionally, both drugs are linked to a condition called hyponatraemia (low blood sodium), particularly in older patients.
What you should do
It is generally safe to take these together, but you should be mindful of how you feel. If you feel dizzy or lightheaded, sit or lie down until the feeling passes. Rise slowly from a sitting or lying position. If you experience persistent dizziness, confusion, or extreme tiredness, mention it to your doctor, as they may want to check your blood pressure or perform a simple blood test to check your salt levels.
Seguir leyendo
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Tratamiento y medicación
Can I take Esomeprazole and Trazodone together?
Esomeprazole may reduce the amount of trazodone that your body absorbs. This could potentially make trazodone less effective at treating your symptoms (such as depression or sleep issues). Additionally, both medications can rarely affect the electrical activity of your heart, though this risk is generally low.

Tratamiento y medicación
Can I take Citalopram and Co codamol together?
Taking these two medicines together can increase the risk of a rare but serious condition called serotonin syndrome. It can also make you feel more drowsy or dizzy than usual. Additionally, citalopram may slightly reduce how well the codeine part of the co-codamol works to relieve your pain.
Seguir leyendo
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

Pregunte, comparta, conecte.
Explore debates, formule preguntas y comparta experiencias sobre cientos de temas de salud.

¿Se encuentra mal?
Evalúe sus síntomas en línea de forma gratuita
Suscríbase al boletín informativo para pacientes.
Tu dosis semanal de consejos de salud claros y fiables, redactados para ayudarte a sentirte informado, seguro y en control.
Al suscribirte, aceptas nuestra Política de privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.