Can I take Losartan and Tizanidine together?
Drug interaction guide
Originally published 25 Jan 2026
Satisface las necesidades del paciente directrices editoriales
- DescargarDescargar
- Compartir
- Idioma
- Debate
Taking these two medicines together can cause your blood pressure to drop too low. This may make you feel very dizzy, lightheaded, or faint, especially when you stand up quickly from a sitting or lying position. It can also make you feel more drowsy or sleepy than usual.
En este artículo:
Seguir leyendo
Why this happens
Both medicines have the effect of lowering blood pressure, though they do it in different ways. Losartan is specifically for blood pressure, while tizanidine is a muscle relaxant that also has a strong blood-pressure-lowering effect. When used together, their effects add up (an additive effect), which can lead to an excessive drop in blood pressure.
What you should do
You should use this combination with caution. When you first start taking them together, or if your dose is increased, be careful when standing up. Move slowly to give your body time to adjust. If you feel very dizzy, faint, or unusually sleepy, contact your doctor. They may need to adjust your doses or monitor your blood pressure more closely.
Seguir leyendo
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Tratamiento y medicación
Can I take Ibuprofen gel 10% and Shortec together?
Using ibuprofen gel alongside Shortec (oxycodone) is generally safe, but there is a small risk of increased side effects such as drowsiness, dizziness, or stomach irritation if the ibuprofen is absorbed into the bloodstream in significant amounts.

Tratamiento y medicación
Can I take Clarithromycin and Rosuvastatin together?
Taking these two medicines together can significantly increase the amount of rosuvastatin in your blood. This increases the risk of serious muscle damage (rhabdomyolysis), which can lead to kidney problems. Symptoms to watch for include unexplained muscle pain, tenderness, or weakness, especially if you also feel generally unwell or have a fever.
Seguir leyendo
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

Pregunte, comparta, conecte.
Explore debates, formule preguntas y comparta experiencias sobre cientos de temas de salud.

¿Se encuentra mal?
Evalúe sus síntomas en línea de forma gratuita
Suscríbase al boletín informativo para pacientes.
Tu dosis semanal de consejos de salud claros y fiables, redactados para ayudarte a sentirte informado, seguro y en control.
Al suscribirte, aceptas nuestra Política de privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.