Can I take Losartan and Tizanidine together?

Por qué sucede esto

Both medicines have the effect of lowering blood pressure, though they do it in different ways. Losartan is specifically for blood pressure, while tizanidine is a muscle relaxant that also has a strong blood-pressure-lowering effect. When used together, their effects add up (an additive effect), which can lead to an excessive drop in blood pressure.

You should use this combination with caution. When you first start taking them together, or if your dose is increased, be careful when standing up. Move slowly to give your body time to adjust. If you feel very dizzy, faint, or unusually sleepy, contact your doctor. They may need to adjust your doses or monitor your blood pressure more closely.

Presión arterial baja (Hipotensión)

Both medicines lower blood pressure. Taking them together significantly increases the risk of severe dizziness, fainting, or a sudden drop in blood pressure when standing up.

Embarazo

No debe tomar losartán si está embarazada. Puede causar daños graves o la muerte de un bebé no nacido, especialmente si se toma durante el segundo y tercer trimestre.

Problemas del hígado

Tizanidine can cause serious liver damage. You will need regular blood tests to check your liver function, and you must report any yellowing of the skin or eyes (jaundice) or severe nausea immediately.

Interrupción repentina del tratamiento

Do not stop taking tizanidine suddenly. Doing so can cause a rapid increase in heart rate and dangerously high blood pressure. Your dose must be reduced gradually.

Alcohol

Es mejor evitar o limitar estrictamente el consumo de alcohol mientras toma losartán. El alcohol puede aumentar el efecto de reducción de la presión arterial del losartán, lo que puede hacer que se sienta mareado, aturdido o débil, especialmente al ponerse de pie. Combinar alcohol con medicación también aumenta el riesgo de daño hepático.

It is best to avoid or strictly limit alcohol while taking tizanidine. Alcohol can significantly increase the sedative effects of this medicine, making you feel extremely drowsy or dizzy, and increases the risk of accidental injury.

Alimentos ricos en potasio (por ejemplo, plátanos, espinacas, sustitutos de la sal)

Losartán puede aumentar los niveles de potasio en su sangre. Debe evitar el uso de sustitutos de sal que contengan potasio (como Lo-Salt) y consultar a su médico antes de aumentar significativamente su ingesta de alimentos ricos en potasio, ya que niveles altos de potasio pueden afectar el ritmo de su corazón.

Caffeine (e.g. coffee, tea, energy drinks, cola)

Caffeine can interfere with how your body breaks down tizanidine, leading to higher levels of the medicine in your blood. This can increase the risk of side effects like extreme drowsiness, dry mouth, and low blood pressure. Try to limit your caffeine intake while taking this medicine.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.