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Can I take Amlodipine and Paracetamol together?

Guía de interacción de medicamentos

There is no known interaction between amlodipine and paracetamol. It is generally considered safe to take these two medicines together.

You can take these medicines together as prescribed. Amlodipine y paracetamol are processed by different pathways in the body and do not interfere with how the other works.

Amlodipine works by relaxing blood vessels to lower blood pressure, while paracetamol works on the central nervous system to reduce pain and fever.

Always follow the dosage instructions on the packaging or as advised by your doctor or pharmacist.

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Precauciones importantes

Liver disease or heavy alcohol consumption

Paracetamol is processed by the liver. If you have liver problems or drink large amounts of alcohol, you are at a much higher risk of fatal liver damage even at standard doses. Never exceed the maximum dose of 8 tablets (4g) in 24 hours.

Severe heart disease (aortic stenosis)

Amlodipine can cause a dangerous drop in blood pressure if you have severe narrowing of the aortic heart valve (estenosis aórtica), which may lead to fainting or heart failure.

Jugo de toronja

Grapefruit juice can increase the amount of amlodipine in your blood. This may cause your blood pressure to drop too low and increase the risk of side effects like headaches or swollen ankles.

While a small glass is unlikely to cause problems for most people, it is best to avoid large amounts of grapefruit juice while taking this medicine.

Alcohol

You can usually drink alcohol in moderation while taking these medicines. However, for amlodipine, alcohol can increase the blood-pressure lowering effect, which might make you feel dizzy or lightheaded.

For paracetamol, chronic heavy drinking increases the risk of liver damage.

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Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 25 Ene 2026 | Publicado originalmente
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