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¿Puedo tomar Propranolol e Ibuprofeno juntos?

Guía de interacción de medicamentos

Tomar ibuprofeno puede hacer que el propranolol sea menos efectivo para reducir la presión arterial. Además, usar estos dos medicamentos juntos puede aumentar el riesgo de problemas renales, especialmente si eres mayor o ya tienes problemas renales.

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Por qué sucede esto

Propranolol works by blocking certain receptors to lower blood pressure. Ibuprofen belongs to a group of drugs (NSAIDs) that cause the body to retain salt and water and can narrow blood vessels in the kidneys. These actions directly oppose the blood-pressure-lowering effects of propranolol.

If you only need a single dose of ibuprofen, the risk is low. However, if you need regular pain relief, speak to your doctor or pharmacist. They may suggest an alternative like paracetamol. If you must take both, monitor your blood pressure regularly and watch for signs of fluid retention, such as swollen ankles.

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Asma o EPOC

You must not take propranolol if you have asthma or a history of wheezing. It can cause a life-threatening narrowing of the airways (bronchospasm).

No tome ibuprofeno si tiene asma, ya que puede causar un empeoramiento potencialmente mortal de su respiración o una reacción alérgica grave.

Stomach ulcers or gastritis

Do not take ibuprofen if you have ever had a stomach ulcer, perforation, or bleeding. It significantly increases the risk of serious internal bleeding.

Embarazo (tercer trimestre)

Do not take ibuprofen if you are more than 28 weeks pregnant. It can cause serious heart and kidney problems in the unborn baby and complications during birth.

Diabetes

Propranolol can hide the early warning signs of low blood sugar (hypoglycaemia), such as a fast heartbeat or tremors. You will need to monitor your blood sugar more closely.

Stopping treatment

Do not stop taking propranolol suddenly. Doing so can cause a dangerous rebound increase in blood pressure or worsen heart conditions. Your dose must be reduced gradually by a doctor.

Alcohol

Drinking alcohol while taking propranolol can increase the medicine's blood-pressure-lowering effect, which may make you feel dizzy or lightheaded. It is best to limit or avoid alcohol, especially when you first start treatment or if your dose is increased.

It is best to avoid or strictly limit alcohol while taking ibuprofen. Combining alcohol with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen increases the risk of irritation to your stomach lining and can lead to stomach ulcers or bleeding.

Cafeína

Propranolol is often used to treat physical symptoms of anxiety or heart palpitations. Caffeine (found in coffee, tea, and energy drinks) is a stimulant that can increase your heart rate and blood pressure, potentially working against the effects of your medicine.

Alimentos (General)

Propranolol can be taken with or without food, but you should be consistent. Taking it with food can increase the amount of medicine absorbed by your body. It is best to always take it the same way (either always with food or always without) to keep your blood levels steady.

Se recomienda tomar ibuprofeno con alimentos o un vaso de leche para reducir el riesgo de malestar estomacal o indigestión.

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Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 24 Ene 2026 | Publicado originalmente
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