Capsulas y gotas de Alfacalcidol
One-Alpha
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 23 de agosto de 2024
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Alfacalcidol is a type of vitamin D.
You will need to have regular blood tests while you are taking the medicine so that your doctor can adjust your dose.
Make sure you know the symptoms of too much calcium in your blood - these are losing your appetite, feeling thirsty, being sick (vomiting), feeling tired and losing weight. Please let your doctor know if you develop these symptoms.
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About alfacalcidol
Tipo de medicamento | A type of vitamin D |
Usado para | To promote healthy bones |
También llamado | One-Alpha®; AlfaD®;AlciDol®; AlfacalEss®; |
Disponible como | Capsules, oral drops and injection |
Alfacalcidol is a type of vitamin D. Vitamin D helps to regulate the amount of calcium and phosphate in your body. All three of these substances are important for maintaining healthy, strong bones and teeth.
There are several types of vitamin D available but most other types need 'activating' by the kidneys. Alfacalcidol is a form of vitamin D which does not need this activation process, and so it is particularly helpful for people who need their bones strengthening but who also have kidney problems. You may also need to take mineral supplements along with alfacalcidol.
Alfacalcidol is available as capsules, as oral liquid drops and also as an injection.
Before taking alfacalcidol
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking alfacalcidol it is important that your doctor knows:
Si estás embarazada o amamantando.
If you have ever had kidney stones or you have other problems with your kidneys.
If you know you have too much calcium in your blood or urine. This can happen with some cancers.
If you have any heart problems.
If you have an allergy to sesame oil (used in One-Alpha® capsules).
If you have been told you have sarcoidosis or other rare, 'granulomatous' disease.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take alfacalcidol
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about alfacalcidol and will provide you with a full list of the side-effects which you may experience from taking it.
Take alfacalcidol exactly as your doctor tells you to. It is usually taken as one dose a day. Try to take your doses at the same time of day each day, as this will help you to remember to take it regularly.
There are three strengths of capsule and one strength of oral drop available - your doctor will tell you what dose to take each day. Your dose could change from time to time depending upon the results of your routine blood tests.
Si olvida tomar una dosis, tómela tan pronto como lo recuerde. Si no lo recuerda hasta el día siguiente, omita la dosis olvidada. No tome dos dosis juntas para compensar una dosis olvidada.
Directions for using One-Alpha® drops
Nota: each drop contains 0.1 microgram (100 nanograms) of alfacalcidol.
Remove the bottle cap. (Do reportado shake the bottle before using.) You will see a dropper which is ready for you to use.
Hold the bottle upside down so that a drop appears at the end of the dropper. If a drop doesn't form, tap the bottle gently with a finger so that it does.
Let the drop fall into your (or your child's) mouth, or catch it on a spoon if this is easier. Your doctor will tell you how many drops to take - count these out carefully to make sure that you (or your child) take the correct number.
Obteniendo el máximo de tu tratamiento
Volver al contenidoTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have regular blood tests during the treatment to check on the amount of calcium in your blood. Your dose of alfacalcidol will be adjusted as a result of having these tests.
Treatment with alfacalcidol may be for short periods of time (such as in preparation for surgery), or could be long-term. Please continue to take alfacalcidol regularly unless you are told otherwise by your doctor.
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Can alfacalcidol cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Alfacalcidol occasionally causes skin rashes but other side-effects could be due to too much calcium being in your blood (see the table below). You will find a full list of side-effects in the manufacturer's information leaflet supplied with your medicine. Please speak with your doctor or pharmacist if any of the following continue or become troublesome.
Alfacalcidol side-effects | ¿Qué puedo hacer si experimento esto? |
Skin rash and itchiness | Si es problemático, hable con su médico |
Sensación de mareo | Do not drive and do not use tools or machines until you are feeling better |
Loss of appetite, loss of weight, feeling tired, feeling sick (nausea), feeling thirsty, sweating, a metallic taste in your mouth, a need to pass urine more often | These are signs that there could be too much calcium in your blood. Make an appointment to see your doctor as soon as possible. Your dose may need adjusting or your treatment with alfacalcidol may need to be stopped for a few days |
If you experience any other symptoms which you think may be due to alfacalcidol, please speak with your doctor or pharmacist for further advice.
How to store alfacalcidol
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Capsules should be stored in a cool, dry place, away from direct heat and light.
Oral drops should be kept refrigerated once the bottle has been opened. Do not use or keep an opened bottle for longer than 28 days.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Si compras algún medicamento, consulta con un farmacéutico que sean adecuados para tomar con tus otros medicamentos.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, One-Alpha® Capsules; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated February 2022.
- Manufacturer's PIL, One-Alpha® oral drops; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated February 2022.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Siguiente revisión prevista: 25 de agosto de 2027
23 de agosto de 2024 | Última versión

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