Artritis psoriásica
Última actualización 18 Aug 2020
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Psoriatic arthritis is a condition involving joint inflammation (arthritis) that usually occurs in combination with a skin disorder called psoriasis. Psoriasis is a chronic inflammatory condition characterised by patches of red, irritated skin that are often covered by flaky white scales. People with psoriasis may also have changes in their fingernails and toenails, such as nails that become pitted or ridged, crumble, or separate from the nail beds.
Descripción
Psoriatic arthritis is a condition involving joint inflammation (arthritis) that usually occurs in combination with a skin disorder called psoriasis. Psoriasis is a chronic inflammatory condition characterised by patches of red, irritated skin that are often covered by flaky white scales. People with psoriasis may also have changes in their fingernails and toenails, such as nails that become pitted or ridged, crumble, or separate from the nail beds.
Signs and symptoms of psoriatic arthritis include stiff, painful joints with redness, heat, and swelling in the surrounding tissues. When the hands and feet are affected, swelling and redness may result in a "sausage-like" appearance of the fingers or toes (dactylitis).
In most people with psoriatic arthritis, psoriasis appears before joint problems develop. Psoriasis typically begins during adolescence or young adulthood, and psoriatic arthritis usually occurs between the ages of 30 and 50. However, both conditions may occur at any age. In a small number of cases, psoriatic arthritis develops in the absence of noticeable skin changes.
Psoriatic arthritis may be difficult to distinguish from other forms of arthritis, particularly when skin changes are minimal or absent. Nail changes and dactylitis are two features that are characteristic of psoriatic arthritis, although they do not occur in all cases.
Psoriatic arthritis is categorized into five types: distal interphalangeal predominant, asymmetric oligoarticular, symmetric polyarthritis, spondylitis, and arthritis mutilans.
The distal interphalangeal predominant type affects mainly the ends of the fingers and toes. The distal interphalangeal joints are those closest to the nails. Nail changes are especially frequent with this form of psoriatic arthritis.
The asymmetric oligoarticular and symmetric polyarthritis types are the most common forms of psoriatic arthritis. The asymmetric oligoarticular type of psoriatic arthritis involves different joints on each side of the body, while the symmetric polyarthritis form affects the same joints on each side. Any joint in the body may be affected in these forms of the disorder, and symptoms range from mild to severe.
Some individuals with psoriatic arthritis have joint involvement that primarily involves spondylitis, which is inflammation in the joints between the vertebrae in the spine. Symptoms of this form of the disorder involve pain and stiffness in the back or neck, and movement is often impaired. Joints in the arms, legs, hands, and feet may also be involved.
The most severe and least common type of psoriatic arthritis is called arthritis mutilans. Fewer than 5 percent of individuals with psoriatic arthritis have this form of the disorder. Arthritis mutilans involves severe inflammation that damages the joints in the hands and feet, resulting in deformation and movement problems. Bone loss (osteolysis) at the joints may lead to shortening (telescoping) of the fingers and toes. Neck and back pain may also occur.
Patrones de herencia
The source lists the following possible inheritance patterns: Pattern unknown. More than one pattern can apply in different cases.
Related genes
Otros nombres
Arthropathic psoriasis
Artritis psoriásica
Related patient information and medicines
Patient information leaflet
Artritis psoriásica
Psoriatic arthritis causes inflammation, pain and swelling of joints in some people who have psoriasis. Other parts of the body may also be affected. For example, inflammation may also affect tendons and ligaments. Surgery is sometimes needed if a joint or tendon becomes badly damaged. What is psoriatic arthritis. Psoriatic arthritis is a.
Patient information leaflet
Artritis
Arthriti... Psoriatic arthritis Psoriatic arthritis causes inflammation, pain, and swelling of joints in some people who have psoriasis (a skin condition). Other parts of the body may also be affected. For example, inflammation may also affect tendons and ligaments. The severity can vary from mild to severe. In some cases, affected joints become.
Patient information leaflet
Dolor articular
This leaflet summarises the most common causes of joint pain, and discusses when you should seek help if you have joint pain. There are links to many of the specific conditions which cause joint pain. See the separate leaflet called Rheumatoid arthritis. Psoriatic arthritis Causes inflammation, pain, and swelling of joints in some people who have.
Patient information leaflet
Artritis idiopática juvenil
Juvenile idiopathic arthritis is a condition in which persisting joint inflammation first occurs in children under the age of 16 years. Juvenile psoriatic arthritis. Arthritis occurs with a skin condition llamado psoriasis or there is arthritis plus at least two of: Inflammation of a finger or toe, causing pain and swelling. A family history of.
Patient information leaflet
La psoriasis
The problems include the following: Joint problems At least 1 or 2 out of every 10 people with psoriasis also develop inflammation and pains in some joints (arthritis). This is called psoriatic arthritis. Any joint can be affected, but it most commonly affects the joints of the fingers and toes. The cause of this is not clear. See the separate.
Patient information leaflet
Psoriasis ungueal
Psoriatic nail disease is a type of psoriasis. Psoriasis is a common skin condition that usually causes patches (plaques) of red, scaly skin but sometimes affects the nails and cuticles. There is also a form of arthritis that is linked to psoriasis, llamado psoriatic arthritis. Psoriatic nail disease is particularly common if you have psoriatic.
Lecturas adicionales y referencias
- Artritis psoriásica; MedlinePlus, National Library of Medicine.
- Castelino M, Barton A. Genetic susceptibility factors for psoriatic arthritis. Curr Opin Rheumatol. 2010 Mar;22(2):152-6. doi: 10.1097/BOR.0b013e32833669d2.
- Chandran V, Raychaudhuri SP. Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis. J Autoimmun. 2010 May;34(3):J314-21. doi: 10.1016/j.jaut.2009.12.001. Epub 2009 Dec 24.
- Gladman DD. Psoriatic arthritis. Dermatol Ther. 2009 Jan-Feb;22(1):40-55. doi: 10.1111/j.1529-8019.2008.01215.x.
- Jordan CT, Cao L, Roberson ED, Pierson KC, Yang CF, Joyce CE, Ryan C, Duan S, Helms CA, Liu Y, Chen Y, McBride AA, Hwu WL, Wu JY, Chen YT, Menter A, Goldbach-Mansky R, Lowes MA, Bowcock AM. PSORS2 is due to mutations in CARD14. Am J Hum Genet. 2012 May 4;90(5):784-95. doi: 10.1016/j.ajhg.2012.03.012. Epub 2012 Apr 19.
- McGonagle D, Benjamin M, Tan AL. The pathogenesis of psoriatic arthritis and associated nail disease: not autoimmune after all? Curr Opin Rheumatol. 2009 Jul;21(4):340-7. doi: 10.1097/BOR.0b013e32832c6ab9.
- McGonagle D, Palmou Fontana N, Tan AL, Benjamin M. Nailing down the genetic and immunological basis for psoriatic disease. Dermatology. 2010;221 Suppl 1:15-22. doi: 10.1159/000316171. Epub 2010 Aug 9.
- Nograles KE, Brasington RD, Bowcock AM. New insights into the pathogenesis and genetics of psoriatic arthritis. Nat Clin Pract Rheumatol. 2009 Feb;5(2):83-91. doi: 10.1038/ncprheum0987.
- O'Rielly DD, Rahman P. Where do we stand with the genetics of psoriatic arthritis? Curr Rheumatol Rep. 2010 Aug;12(4):300-8. doi: 10.1007/s11926-010-0111-4.
- Ritchlin C. Psoriatic disease--from skin to bone. Nat Clin Pract Rheumatol. 2007 Dec;3(12):698-706. doi: 10.1038/ncprheum0670.
- Wollina U, Unger L, Heinig B, Kittner T. Psoriatic arthritis. Dermatol Ther. 2010 Mar-Apr;23(2):123-36. doi: 10.1111/j.1529-8019.2010.01306.x.
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