¿Puedo tomar Co-codamol y Sertralina juntos?

Caution is advised when taking co-codamol y sertralina together as combining them can increase the risk of síndrome serotoninérgico.

Always speak to your doctor before combining these medicines.

Cómo funcionan

Both drugs affect a chemical in the brain called serotonin; when levels get too high, it causes side effects.

Sertraline blocks a specific liver enzyme (CYP2D6) that the body needs to convert codeine into morphine. If this conversion doesn't happen, the pain-killing effect is lost.

• Speak to your doctor before taking these medicines.

• If you must take both, be alert for signs of serotonin syndrome, such as shivering, diarrhoea, fever, sweating, or muscle stiffness.

• If you find that co-codamol is not helping your pain, your doctor may suggest an alternative painkiller such as paracetamol (without codeine) or ibuprofen.

Trastornos de depresión y ansiedad

Es posible que experimente un aumento en los pensamientos suicidas o el impulso de autolesionarse al comenzar a tomar sertralina o al cambiar la dosis. Esto es más frecuente en adultos jóvenes menores de 25 años. Comuníquese con su médico o acuda a un hospital de inmediato si nota cambios en su estado de ánimo o comportamiento.

Síndrome serotoninérgico

Taking these together increases the risk of serotonin syndrome, a potentially life-threatening condition. Seek immediate medical help if you experience agitation, hallucinations, rapid heart rate, or severe muscle twitching.

sobredosis de paracetamol

Co-codamol contains paracetamol. Do not take it with any other paracetamol-containing products (such as cold and flu remedies), as this can lead to fatal liver damage.

Adicción a los opioides y abstinencia

Co-codamol contains codeine, which can cause addiction if used for more than 3 days. Stopping suddenly after long-term use can cause withdrawal symptoms.

Dificultades respiratorias

No tome co-codamol si tiene asma severa o problemas respiratorios, ya que la codeína puede ralentizar peligrosamente su respiración.

Aumento del riesgo de sangrado

Sertraline increases your risk of serious bleeding, especially in the stomach. This risk is significantly higher if you also take aspirin, ibuprofen (NSAIDs), or blood-thinning medications such as warfarin.

Niveles bajos de sodio (hiponatremia)

La sertralina puede causar una caída grave en los niveles de sodio en la sangre, especialmente en pacientes mayores o que toman diuréticos. Busque ayuda médica si experimenta confusión extrema, debilidad o dificultad para caminar.

Alcohol

You must avoid drinking alcohol while taking co-codamol. Combining alcohol with codeine increases the risk of serious side effects, such as extreme sleepiness, breathing difficulties, and loss of consciousness. Additionally, both alcohol and paracetamol can affect the liver; combining them regularly increases the risk of liver damage.

It is best to avoid or strictly limit alcohol while taking sertraline. Combining alcohol with this medicine can increase side effects such as drowsiness, dizziness, and impaired coordination. It may also make your depression or anxiety symptoms worse.

Jugo de toronja

Grapefruit juice can interfere with how your body processes codeine, potentially making the medicine less effective or increasing the risk of side effects. It is best to avoid grapefruit juice while taking this medicine. Avoid drinking large amounts of grapefruit juice. Grapefruit can increase the levels of sertraline in your blood, which may increase the risk of side effects.

Cafeína

Some versions of co-codamol already contain caffeine. If you consume extra caffeine from coffee, tea, or energy drinks, it may make you feel shaky, anxious, or cause a racing heart.

La sertralina puede causar nerviosismo o temblores en ocasiones. Consumir grandes cantidades de cafeína puede empeorar estos efectos secundarios o aumentar los sentimientos de ansiedad. Se recomienda controlar su ingesta de cafeína.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.