Can I take Clopidogrel and Paracetamol together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no significant interaction between clopidogrel and paracetamol. It is generally considered the safest painkiller to take while on blood-thinning medication.
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Why this happens
Clopidogrel works by preventing platelets from sticking together to form clots. Paracetamol works on pain signals in the central nervous system and does not affect platelet function or the lining of the stomach, meaning it does not increase the risk of bleeding.
What you should do
You can safely take paracetamol at the recommended dose while taking clopidogrel. However, you should avoid anti-inflammatory painkillers like ibuprofen or aspirin (unless specifically prescribed by your doctor), as these can significantly increase your risk of bleeding when combined with clopidogrel.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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