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Can I take Atorvastatin and Metformin together?

Drug interaction guide

There is no significant direct interaction between atorvastatin and metformin. Both medications are commonly prescribed together to manage cholesterol and blood sugar levels in patients with type 2 diabetes.

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Why this happens

Atorvastatin and metformin are processed by different pathways in the body. Atorvastatin is primarily broken down by the liver (CYP3A4 enzyme), while metformin is cleared by the kidneys. They do not interfere with each other's absorption or metabolism.

What you should do

You can safely take these medications together as prescribed by your doctor. It is important to continue taking both to manage your heart health and blood sugar levels. If you experience unusual muscle pain or weakness (a rare side effect of statins), you should still report this to your doctor.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • 25 Enero 2026 | Publicado originalmente
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