Can I take Black cohosh and Folic acid together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between black cohosh and folic acid. It is generally considered safe to take these two supplements together.
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Why this happens
Black cohosh and folic acid are processed by the body through different pathways. Black cohosh is primarily broken down by liver enzymes (specifically the CYP450 system), while folic acid is a water-soluble B vitamin that follows a separate metabolic route. They do not interfere with each other's absorption or effectiveness.
What you should do
You can continue to take both supplements as directed. However, always inform your doctor or pharmacist about all supplements you are taking, especially if you have a history of liver problems or are pregnant, as black cohosh may not be suitable for everyone.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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