Can I take Amlodipine/ valsartan and Atenolol together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these medicines together can cause your blood pressure to drop too low (hypotension) or your heart rate to slow down too much (bradycardia). You might feel dizzy, lightheaded, faint, or unusually tired.
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Why this happens
All three medicines work to lower blood pressure and reduce the workload on your heart, but they do it in different ways. Amlodipine relaxes blood vessels, valsartan blocks a hormone that narrows vessels, and atenolol slows the heart rate. When combined, their effects add together, which can sometimes be too powerful.
What you should do
You can take these together if they have been prescribed by your doctor, but you should monitor your blood pressure and heart rate regularly at home. Be careful when standing up quickly from a sitting or lying position. If you feel very dizzy, faint, or notice a very slow pulse, contact your doctor.
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Important precautions
Asthma or COPD
Do not take this medicine if you have asthma, wheezing, or chronic obstructive pulmonary disease (COPD). It can cause a severe, potentially life-threatening narrowing of the airways.
Food and drink warnings
Alcohol
Drinking alcohol while taking these blood pressure medicines can cause an additive effect, making you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep alcohol intake within recommended limits and see how the medicine affects you first.
Orange Juice and Apple Juice
Drinking large amounts of orange or apple juice may reduce the amount of atenolol absorbed by your body, potentially making it less effective. It is best to avoid drinking large quantities of these juices at the same time as taking your tablet.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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