Peters anomaly
Última actualización 2 Jul 2025
Cumple con las directrices editoriales
- DescargarDescargar
- Compartir
- Language
- Discusión
- Versión en audio
- Agregar a fuentes preferidas en Google
Peters anomaly is characterised by eye problems that occur in an area at the front part of the eye known as the anterior segment. The anterior segment consists of structures including the lens, the colored part (iris) of the eye, and the clear covering of the eye (cornea). During development of the eye, the elements of the anterior segment form separate structures. However, in Peters anomaly, development of the anterior segment is abnormal, leading to incomplete separation of the cornea from the iris or the lens. As a result, the cornea is cloudy (opaque), which causes blurred vision. The opaque area (opacity) of the cornea varies in size and intensity from a small, faint streak to a large, white cloudy area that covers the front surface of the eye. Additionally, the location of the opacity varies; the cloudiness may be at the center of the cornea or off-center. Large, centrally located opacities tend to cause poorer vision than smaller, off-center ones.
Descripción
Peters anomaly is characterised by eye problems that occur in an area at the front part of the eye known as the anterior segment. The anterior segment consists of structures including the lens, the colored part (iris) of the eye, and the clear covering of the eye (cornea). During development of the eye, the elements of the anterior segment form separate structures. However, in Peters anomaly, development of the anterior segment is abnormal, leading to incomplete separation of the cornea from the iris or the lens. As a result, the cornea is cloudy (opaque), which causes blurred vision. The opaque area (opacity) of the cornea varies in size and intensity from a small, faint streak to a large, white cloudy area that covers the front surface of the eye. Additionally, the location of the opacity varies; the cloudiness may be at the center of the cornea or off-center. Large, centrally located opacities tend to cause poorer vision than smaller, off-center ones.
Nearly half of the individuals affected with Peters anomaly have low vision early in life and about a quarter are legally blind. Due to a lack of visual stimulation, some individuals develop "lazy eye" (amblyopia). Peters anomaly is often associated with other eye problems, such as increased pressure within the eye (glaucoma), clouding of the lens (cataract), and unusually small eyeballs (microphthalmia). In most cases, Peters anomaly is bilateral, which means that it affects both eyes, although the level of vision impairment may be different in each eye. These individuals may have eyes that do not point in the same direction (strabismus). In some people with Peters anomaly, corneal clouding improves over time leading to improved vision.
There are two types of Peters anomaly, which are distinguished by their signs and symptoms. Peters anomaly type I is characterised by an incomplete separation of the cornea and iris and mild to moderate corneal opacity. Type II is characterised by an incomplete separation of the cornea and lens and severe corneal opacity that may involve the entire cornea.
Patrones de herencia
The source lists the following possible inheritance patterns: Autosomal recessive; Autosomal dominant. More than one pattern can apply in different cases.
Related genes
Otros nombres
Irido-corneo-trabecular dysgenesis
Peters congenital glaucoma
Related patient information and medicines
Patient information leaflet
Viajar a lugares remotos
If you consider that you might need 'j... Personal first aid kit for a remote trip The following lists a comprehensive first aid kit for two people travelling together to a remote environment. It is based on the advice given in 'Pocket First Aid and Wilderness Medicine', a book written by two well-established expedition doctors with experience of.
Patient information leaflet
pruebas de detección durante el embarazo
This leaflet discusses the routine pregnancy screening tests (antenatal checks) that should be offered to all pregnant women in the UK. These are screening an... A pregnancy screening test (also known as an prenatal check), aims to detect a disease or condition in the early stages before it causes significant problems, and where treatment can be.
Patient information leaflet
Programa de cribado del NHS
Detección involves tests on people without symptoms to check if they have a disease or condition before it causes symptoms. The reason for screening is the expectation that a problem can be discovered in the early stages and either prevented from progressing further or treated before they cause significant problems. Not all conditions have.
Patient information leaflet
Muestreo de vellosidades coriónicas
Muestreo de vellosidades coriónicas (CVS) is a procedure that is carried out during pregnancy to diagnose or exclude various chromosomal or genetic conditions. Chorionic villus sampling (CVS) is a procedure that is carried out during early pregnancy. Usually the reason is to see if the developing baby has a chromosomal disorder such as Down's syndrome or a.
Patient information leaflet
Amniocentesis
The most common reason for a pregnant woman to be offered amniocentesis is to see if a developing baby has a chromosomal disorder such as Down's syndrome. Amniocentesis is a procedure that is carried out during pregnancy. The most common reason for a pregnant woman to be offered amniocentesis is to see if her developing baby has a chromosomal.
Patient information leaflet
Estrabismo en niños
A squint is a condition where the eyes do not always look in exactly the same direction. What is a squint. A squint, also called strabismus, is a condition where the eyes do not line up perfectly together in the direc... A child with a squint may stop processing information from the affected eye, so that it effectively stops seeing. This can lead.
Lecturas adicionales y referencias
- Peters anomaly; MedlinePlus, National Library of Medicine.
- Bhandari R, Ferri S, Whittaker B, Liu M, Lazzaro DR. Peters anomaly: review of the literature. Cornea. 2011 Aug;30(8):939-44. doi: 10.1097/ICO.0b013e31820156a9.
- Chang JW, Kim JH, Kim SJ, Yu YS. Long-term clinical course and visual outcome associated with Peters' anomaly. Eye (Lond). 2012 Sep;26(9):1237-42. doi: 10.1038/eye.2012.128. Epub 2012 Jun 29.
- Chesneau B, Aubert-Mucca M, Fremont F, Pechmeja J, Soler V, Isidor B, Nizon M, Dollfus H, Kaplan J, Fares-Taie L, Rozet JM, Busa T, Lacombe D, Naudion S, Amiel J, Rio M, Attie-Bitach T, Lesage C, Thouvenin D, Odent S, Morel G, Vincent-Delorme C, Boute O, Vanlerberghe C, Dieux A, Boussion S, Faivre L, Pinson L, Laffargue F, Le Guyader G, Le Meur G, Prieur F, Lambert V, Laudier B, Cottereau E, Ayuso C, Corton-Perez M, Bouneau L, Le Caignec C, Gaston V, Jeanton-Scaramouche C, Dupin-Deguine D, Calvas P, Chassaing N, Plaisancie J. First evidence of SOX2 mutations in Peters' anomaly: Lessons from molecular screening of 95 patients. Clin Genet. 2022 May;101(5-6):494-506. doi: 10.1111/cge.14123. Epub 2022 Feb 27.
- Harissi-Dagher M, Colby K. Anterior segment dysgenesis: Peters anomaly and sclerocornea. Int Ophthalmol Clin. 2008 Spring;48(2):35-42. doi: 10.1097/IIO.0b013e318169526c. No abstract available.
- Najjar DM, Christiansen SP, Bothun ED, Summers CG. Strabismus and amblyopia in bilateral Peters anomaly. J AAPOS. 2006 Jun;10(3):193-7. doi: 10.1016/j.jaapos.2006.01.006.
- Nischal KK. A new approach to the classification of neonatal corneal opacities. Curr Opin Ophthalmol. 2012 Sep;23(5):344-54. doi: 10.1097/ICU.0b013e328356893d.
- Shigeyasu C, Yamada M, Mizuno Y, Yokoi T, Nishina S, Azuma N. Clinical features of anterior segment dysgenesis associated with congenital corneal opacities. Cornea. 2012 Mar;31(3):293-8. doi: 10.1097/ICO.0b013e31820cd2ab.
Únete a la conversación
Comparte tus pensamientos o experiencias con otros en nuestro comunidades de pacientes.
Pregunta, comparte, conecta.
Navega por discusiones, haz preguntas y comparte experiencias en cientos de temas de salud.
Suscríbete al boletín de Patient
Tu dosis semanal de consejos de salud claros y confiables, escritos para ayudarte a sentirte informado, seguro y en control.
Al suscribirte aceptas nuestros Política de Privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.