Sevelamer tablets and sachets
Renagel, Renvela
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 10 Dic 2024
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Take sevelamer three times a day with meals.
Remember to follow any dietary advice you have been given about what to eat.
De un vistazo
Sevelamer is a medicine used to control high phosphate levels in the blood.
It is for people with severe kidney disease whose kidneys are not working properly.
Sevelamer works by combining with phosphates from food, reducing their absorption.
Take sevelamer with or just after each main meal.
Do not chew or break tablets; swallow them whole.
Do not take two doses if you forget one.
You will have blood tests regularly to check your phosphate levels.
About sevelamer
Tipo de medicamento | A phosphate-binding agent |
Usado para | To control levels of phosphate in the blood |
También llamado | Renagel® (contains sevelamer hydrochloride); Renvela® (contains sevelamer carbonate) |
Disponible como | Tablets and sachets containing powder |
People with severe enfermedad renal can have high levels of phosphate in the blood because their kidneys are not working properly. This excess phosphate can then be deposited in the body and can lead to complications. Sevelamer works by combining with the phosphates that are eaten in food. This reduces the overall amount of phosphate in the blood and helps to reduce the problems that it can cause.
Before taking sevelamer
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking sevelamer it is important that your doctor knows:
Si estás embarazada o amamantando.
If you have any problems with the way your digestive system works. For example, let your doctor know if you have any difficulties swallowing or if you think you could have a blockage in your bowel.
Si está tomando o usando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take sevelamer
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about sevelamer, and will also provide you with a full list of side-effects which you could experience from taking it.
It is usual to take three doses daily. Your doctor will tell you how many tablets or sachets you need to take for each dose. This amount will depend upon how much phosphate is in your blood and will be adjusted to suit you.
Take sevelamer with (or just after) each of your main meals.
If you have been given tablets, do not chew or break them - swallow the tablet whole with a drink of water.
If you have been given sachets, pour the powder from the sachet into a small (60 ml) glass of water and stir it in before you swallow. If you have been told to take more than one sachet for each dose, then do this for each sachet you take. Freshly prepare each dose - you should swallow the suspension within 30 minutes of making it.
The powder can also be mixed with a small amount (100 g) of cold food (such as yoghurt) or juice (120 ml). Do not heat the mixture and do not add the powder to hot food or drinks.
If you forget to take a dose at your usual time, miss the dose out completely. Take your next dose with a meal at the usual time, and then continue as before. Do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need some blood tests every couple of weeks or so to check the amount of phosphate in your body.
Treatment with sevelamer is usually long-term, so continue to take it unless you are advised otherwise by your doctor.
Remember to follow any dietary advice that you have been given by your doctor or dietician. This will also help control the amount of phosphate in your body.
There are two different brands of sevelamer available and it may not be appropriate for you to switch between them. Each time you collect a new supply from your pharmacy, check to see if it is the same brand as you have had before. If it is different, please discuss this with your pharmacist who will advise you.
Can sevelamer cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with sevelamer. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common sevelamer side-effects | ¿Qué puedo hacer si experimento esto? |
Feeling sick (nausea) or being sick (vomiting), tummy (abdominal) pain, indigestion | Stick to simple foods - avoid rich or spicy meals. Make sure you take your doses after meals. If any of these become troublesome, speak with your doctor |
Diarrhoea, constipation, flatulence (wind) | Si alguno de estos se vuelve problemático, hable con su médico |
Si experimenta cualquier otro síntoma que crea que puede deberse al medicamento, por favor hable con su médico o farmacéutico para obtener más consejos.
How to store sevelamer
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Si compras algún medicamento, consulta con un farmacéutico que sea seguro tomarlo junto con tus otros medicamentos.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of the medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
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Informe los efectos secundarios sospechosos de medicamentos, vacunas, cigarrillos electrónicos, incidentes con dispositivos médicos, productos defectuosos o falsificados (falsos) a la Agencia Reguladora de Medicamentos y Productos Sanitarios para garantizar un uso seguro y efectivo.

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Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What is the key difference between Renagel® and Renvela®?
Renagel® contains sevelamer hydrochloride, while Renvela® contains sevelamer carbonate. Both are types of sevelamer, which is a phosphate-binding agent.
Can I take sevelamer at any time of day?
Sevelamer should be taken with, or immediately after, each of your main meals. It works by combining with phosphates in the food you eat.
What should I do if I accidentally chew or break a sevelamer tablet?
Sevelamer tablets should be swallowed whole with a drink of water. The article does not specify what to do if a tablet is accidentally chewed or broken, so it's best to follow the instructions to swallow it whole.
How long will I need to take sevelamer?
Treatment with sevelamer is usually long-term. You should continue to take it unless your doctor advises you otherwise.
What type of cold foods or drinks can the sevelamer powder be mixed with?
The powder can be mixed with a small amount (100g) of cold food, such as yoghurt, or 120ml of juice. It is important not to heat the mixture and not to add the powder to hot food or drinks.
Lecturas adicionales y referencias
- Manufacturer's PIL, Renagel® 800 mg film-coated tablets; Sanofi, The electronic Medicines Compendium. Dated May 2023.
- Manufacturer's PIL, Renvela® 2.4 g Powder for oral suspension; Sanofi, The electronic Medicines Compendium. Dated January 2024.
- Manufacturer's PIL, Renvela® 800 mg film-coated tablets; Sanofi, The electronic Medicines Compendium. Dated January 2024.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Next review due: 10 Dec 2027
10 Dic 2024 | Última versión

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