¿Puedo tomar Sertralina y Trazodona juntos?

You should only take sertralina y trazodone together if they have been specifically prescribed by your doctor. Combining them can increase the risk of síndrome serotoninérgico.

Por qué sucede esto

Both sertraline and trazodone increase the levels of serotonin in the brain. When used together, these effects add up (pharmacodynamic interaction), potentially leading to an overload. Additionally, both drugs can have a sedative effect, which is increased when they are combined.

You may be experiencing an interaction between sertraline and trazodone if you have:

• Agitation or restlessness.

• Confusión.

• Frecuencia cardíaca rápida.

• Sweating more than usual.

• Shivering or goosebumps.

• Muscle twitching or stiffness.

• Diarrea.

• Fiebre.

If you experience any of these symptoms, seek medical help immediately.

• Take them only if your doctor has prescribed them together.

• Be aware of symptoms of serotonin syndrome, such as shivering, sweating, a very high temperature, fast heartbeat, muscle twitching, or agitation.

• Avoid driving or using machinery until you know how this combination affects you.

Pensamientos suicidas y autolesiones

Antidepressants can increase the risk of suicidal thoughts or self-harm, particularly in the first few weeks of treatment or when the dose is changed. Patients and their families should monitor for any changes in mood or behaviour.

Síndrome de serotonina

Taking these medicines together increases the risk of serotonin syndrome, a potentially life-threatening condition. Seek immediate medical help if you experience agitation, hallucinations, rapid heartbeat, shivering, or severe muscle stiffness.

Trastornos de la coagulación

These medicines can increase your risk of bleeding, especially in the stomach. This risk is higher if you also take aspirin, ibuprofen (NSAIDs), or blood-thinning medications like warfarin.

Priapism (prolonged erection)

Trazodone can cause a painful, persistent erection that lasts for several hours. This is a medical emergency; if this occurs, stop taking the medicine and go to an A&E department immediately to avoid permanent damage.

Alcohol

It is best to avoid or strictly limit alcohol while taking these medicines. Combining alcohol with sertraline or trazodone can significantly increase drowsiness, dizziness, and coordination problems. It may also worsen your underlying condition.

Jugo de toronja

Debe evitar consumir grandes cantidades de jugo de pomelo mientras toma sertralina. El pomelo puede aumentar el nivel de sertralina en su sangre, lo que puede incrementar el riesgo de efectos secundarios.

Grapefruit juice can increase the amount of trazodone in your blood, which may increase the risk of side effects like extreme sleepiness or heart rhythm problems. It is best to avoid drinking large amounts of grapefruit juice.

Cafeína (Café, Té, Bebidas Energéticas)

La sertralina a veces puede hacer que te sientas inquieto o tembloroso. Cantidades altas de cafeína pueden empeorar estos sentimientos. Observa cómo te sientes y considera reducir la cafeína si experimentas mayor ansiedad o temblores.

Alimentos (General)

Trazodone should ideally be taken after a meal or a snack. Taking it on an empty stomach can increase the risk of dizziness or lightheadedness.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.