Can I take Felodipine and Grapefruit together?

You must completely avoid grapefruit and grapefruit juice while taking felodipine. Grapefruit significantly increases the amount of felodipine in your blood, which can cause your blood pressure to drop dangerously low and increase the risk of side effects.

Even a single glass of juice or half a grapefruit can significantly increase the amount of the medicine in your bloodstream, and the impact can last for several days.

If you have already consumed grapefruit, monitor your blood pressure and watch for dizziness or a racing heart.

Speak to your doctor or pharmacist about safe fruit alternatives, such as oranges or lemons.

Por qué sucede esto

Your body uses a specific enzyme (called CYP3A4) in the gut and liver to break down felodipine. Grapefruit contains natural compounds that block this enzyme. When the enzyme is blocked, your body cannot clear the medicine properly, leading to much higher levels of the drug than intended.

You may be experiencing an interaction between felodipine and grapefruit (including grapefruit juice) if:

• You feel dizzy or lightheaded, especially when standing up.

• You experience headaches or flushing.

• You notice swelling in your ankles or feet.

• You feel your heart beating faster than usual (palpitaciones).

• You develop low blood pressure symptoms, such as faintness or weakness.

• Symptoms start after eating grapefruit or drinking grapefruit juice while taking felodipine.

Si tienes alguno de los síntomas mencionados, deberías:

• Speak to your GP or pharmacist for advice as soon as possible.

• Avoid grapefruit and grapefruit juice while taking felodipine.

• Do not stop taking felodipine suddenly unless advised by a healthcare professional.

• Seek urgent medical help if you faint or have severe dizziness.

• Attend any blood pressure checks arranged to monitor your treatment.
  

Alcohol

Drinking alcohol while taking felodipine can increase the blood-pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep your alcohol intake to a minimum.

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Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.