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Can I take Citalopram and Ibuprofen together?

Guía de interacción de medicamentos

Taking citalopram and ibuprofen together can increase your risk of internal bleeding, particularly in the stomach or gut. You may notice signs like dark, tarry stools, or stomach pain. While many people take these together without issues, the combination makes your blood less likely to clot and can irritate the stomach lining.

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Por qué sucede esto

Citalopram (an SSRI) reduces the amount of serotonin in your blood platelets, which they need to help blood clot. Ibuprofen (an NSAID) also interferes with clotting and can damage the protective lining of the stomach. When used together, these two effects add up, significantly increasing the risk of a bleed.

Speak to your doctor before taking these together. They may suggest a different painkiller, such as paracetamol, which does not have this interaction. If you must take both, your doctor might prescribe a medicine to protect your stomach. Seek medical help immediately if you vomit blood or notice black, tarry stools.

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Trastornos de depresión y ansiedad

You may experience an increase in suicidal thoughts or the urge to self-harm when first starting this medicine or changing the dose. This is more common in young adults under 25. Contact your doctor or go to hospital immediately if this happens.

Stomach ulcers and bleeding

Taking these medicines together significantly increases your risk of serious stomach bleeding. Seek urgent medical help if you vomit blood or pass black, tarry stools.

Asma

Do not take ibuprofen if you have asthma and have ever experienced wheezing, shortness of breath, or a runny nose after taking aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs).

Trastornos del ritmo cardíaco (Síndrome de QT largo)

Citalopram can affect your heart rhythm. You must not take it if you have a known heart rhythm problem or are taking other medicines that affect the heart's electrical activity.

Low sodium levels (Hyponatraemia)

Citalopram can cause a serious drop in blood sodium levels, especially in the elderly. Seek medical help if you experience extreme tiredness, confusion, or muscle twitching.

Embarazo (tercer trimestre)

No tome ibuprofeno si tiene más de 6 meses de embarazo, ya que puede causar problemas graves de corazón y riñón en el bebé no nacido y complicaciones durante el parto.

Alcohol

It is best to avoid drinking alcohol while taking citalopram. Alcohol can increase the sedative effects of the medicine, making you feel more sleepy or dizzy, and may worsen your depression or anxiety symptoms.

Drinking alcohol while taking ibuprofen can increase the risk of stomach irritation and gastrointestinal bleeding. It is best to limit or avoid alcohol, especially if you are taking ibuprofen regularly or in high doses.

Cafeína (Café, Té, Bebidas Energéticas)

Citalopram can sometimes cause feelings of restlessness or jitteriness, especially when you first start taking it. Caffeine is a stimulant that can worsen these side effects and may increase feelings of anxiety. It is advisable to monitor your caffeine intake.

Alimentos (General)

It is recommended to take ibuprofen with food or a glass of milk. This helps to protect your stomach lining and reduces the risk of indigestion or stomach upset.

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Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 25 Ene 2026 | Publicado originalmente
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