Can I take Alcohol and Paracetamol together?
Drug interaction guide
Originally published 25 Jan 2026
Satisface las necesidades del paciente directrices editoriales
- DescargarDescargar
- Compartir
- Idioma
- Debate
Drinking alcohol while taking paracetamol can increase the risk of serious liver damage. This is particularly dangerous for people who drink alcohol regularly or in large amounts (chronic heavy drinking), but it can also be a concern during a single episode of heavy drinking (binge drinking).
En este artículo:
Seguir leyendo
Why this happens
The liver breaks down paracetamol into a toxic byproduct. Normally, the liver uses a substance called glutathione to neutralise this toxin. Alcohol can deplete the liver's supply of glutathione and also cause the liver to produce more of the toxic byproduct, making it harder for the body to protect itself from liver damage.
What you should do
If you drink more than 3 units of alcohol a day on a regular basis, you must speak to your doctor before taking paracetamol. If you are taking paracetamol for pain, it is best to avoid alcohol entirely. Never exceed the maximum dose of paracetamol (usually 4 grams or eight 500mg tablets in 24 hours), as alcohol makes even a small overdose much more dangerous.
Seguir leyendo
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Tratamiento y medicación
Can I take Clarithromycin and Rosuvastatin together?
Taking these two medicines together can significantly increase the amount of rosuvastatin in your blood. This increases the risk of serious muscle damage (rhabdomyolysis), which can lead to kidney problems. Symptoms to watch for include unexplained muscle pain, tenderness, or weakness, especially if you also feel generally unwell or have a fever.

Tratamiento y medicación
Can I take Esomeprazole and Trazodone together?
Esomeprazole may reduce the amount of trazodone that your body absorbs. This could potentially make trazodone less effective at treating your symptoms (such as depression or sleep issues). Additionally, both medications can rarely affect the electrical activity of your heart, though this risk is generally low.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

Pregunte, comparta, conecte.
Explore debates, formule preguntas y comparta experiencias sobre cientos de temas de salud.

¿Se encuentra mal?
Evalúe sus síntomas en línea de forma gratuita
Suscríbase al boletín informativo para pacientes.
Tu dosis semanal de consejos de salud claros y fiables, redactados para ayudarte a sentirte informado, seguro y en control.
Al suscribirte, aceptas nuestra Política de privacidad. Puedes darte de baja en cualquier momento. Nunca vendemos tus datos.