Can I take Sedoxil and Wellbutrin together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together can make you feel much more sleepy, dizzy, or confused than usual. It can also slow down your breathing and affect your coordination, increasing the risk of falls or accidents.
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Why this happens
Both medicines affect the central nervous system. Sedoxil (mexazolam) is a benzodiazepine that slows down brain activity to reduce anxiety. Wellbutrin (bupropion) is an antidepressant. When used together, their sedative effects add up, leading to increased drowsiness and impaired physical or mental function.
What you should do
You should speak to your doctor before taking these together. If your doctor has prescribed both, be very careful when driving or using machinery. Avoid drinking alcohol, as this will make the sleepiness much worse. Seek medical help immediately if you experience extreme drowsiness or difficulty breathing.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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