¿Puedo tomar Fluanxol y Wellbutrin juntos?
Guía de interacción de medicamentos
Publicado originalmente 25 Ene 2026
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Tomar estos dos medicamentos juntos puede aumentar significativamente su riesgo de tener una convulsión (ataque). Ambos medicamentos también pueden afectar los niveles del otro en su sangre, lo que puede provocar más efectos secundarios como inquietud, temblores o movimientos musculares inusuales.
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Por qué sucede esto
Both Fluanxol (flupentixol) and Wellbutrin (bupropion) lower the 'seizure threshold', meaning they make it easier for a seizure to occur. Additionally, Wellbutrin blocks the liver enzyme (CYP2D6) that breaks down Fluanxol, which can cause Fluanxol to build up to higher, potentially toxic levels in your body.
Lo que deberías hacer
Volver al contenidoYou must speak to your doctor before taking these two medicines together. They may need to adjust your doses or choose an alternative treatment. If you are prescribed both, seek medical help immediately if you experience a seizure, extreme shakiness, or severe agitation.
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Precauciones importantes
Volver al contenidoSeizure disorders or epilepsy
Wellbutrin significantly increases the risk of having a seizure. You must not take it if you have a history of epilepsy, an eating disorder (bulimia or anorexia), or if you are undergoing sudden withdrawal from alcohol or sedatives.
enfermedad de Parkinson
Fluanxol can significantly worsen the symptoms of Parkinson's disease and should generally be avoided.
Trastornos del ritmo cardíaco (Síndrome de QT largo)
Fluanxol can affect your heart rhythm. You must tell your doctor if you have a history of heart rhythm problems or are taking other medicines that affect the heart.
Trastorno bipolar
These medicines can trigger a switch from depression to mania or rapid cycling in people with bipolar disorder. Monitor closely for racing thoughts, extreme energy, or impulsive behaviour.
Advertencias sobre alimentos y bebidas
Volver al contenidoAlcohol
You should avoid or strictly limit alcohol while taking these medicines. Alcohol can increase the sedative effects of Fluanxol, making you very drowsy. More importantly, both Wellbutrin and alcohol (or alcohol withdrawal) can lower the seizure threshold; combining them significantly increases the risk of having a fit (seizure).
Cafeína (Café, Té, Bebidas Energéticas)
Caffeine can interfere with how Fluanxol works. High amounts of caffeine may reduce the effectiveness of the medicine or worsen symptoms of restlessness and anxiety. Try to keep your caffeine intake consistent and moderate.
Wellbutrin is a stimulant. Consuming high amounts of caffeine can increase the risk of side effects such as anxiety, tremors, palpitations, and insomnia. It may also further increase the risk of seizures.
Comidas ricas en grasa
If you are taking the modified-release version of bupropion, taking it with a very high-fat meal can increase the amount of medicine absorbed into your bloodstream, which may increase the risk of side effects. It is best to be consistent in how you take it.
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Uso de otros medicamentos
Volver al contenidoTaking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
25 Ene 2026 | Publicado originalmente

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