Can I take Esomeprazole and Losartan together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no significant interaction between esomeprazole and losartan. Taking these two medicines together is generally considered safe.
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Why this happens
Esomeprazole (a stomach acid reducer) and losartan (a blood pressure medication) are processed by different pathways in the body. Esomeprazole does not significantly interfere with how the liver breaks down losartan, nor does it affect how the kidneys remove it from your system. Furthermore, the reduction in stomach acid caused by esomeprazole does not change how well losartan is absorbed into the bloodstream.
What you should do
You can continue to take both medications as prescribed by your doctor. You do not need to change the timing of your doses or take any special precautions. As always, if you notice any new or unusual symptoms, or if your blood pressure readings change significantly, consult your healthcare professional.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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