Can I take Atorvastatin and Clopidogrel together?

Por qué sucede esto

Both medicines are processed by the same enzyme in the liver (CYP3A4). Because atorvastatin uses this enzyme, it can slow down the process that turns clopidogrel into its active form, potentially making clopidogrel slightly less effective at 'thinning' the blood.

You should continue taking both medicines as prescribed by your doctor. Do not stop taking either medication without medical advice, as they are often prescribed together to protect your heart. Your doctor is likely already aware of this interaction and has determined it is safe for you. If you have concerns, or if you notice any new signs of blood clots (such as sudden leg pain or shortness of breath), speak to your GP.

Embarazo

Do not take atorvastatin if you are pregnant or planning to become pregnant, as it may harm your unborn baby. Use effective contraception while taking this medicine.

Riesgo de sangrado

Clopidogrel increases your risk of serious bleeding. Seek urgent medical help if you have signs of internal bleeding, such as black tarry stools, blood in your urine, or coughing up blood.

Cirugía o trabajo dental

You must tell your surgeon or dentist that you are taking clopidogrel before any procedure, as you may need to stop taking it temporarily to prevent excessive bleeding.

Muscle problems (Myopathy) - atorvastatin

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to serious kidney problems.

Alcohol

It is best to avoid or strictly limit alcohol when taking these medicines. Drinking alcohol with atorvastatin can increase your risk of liver problems and muscle damage. Drinking alcohol with clopidogrel can increase the risk of bleeding in your stomach or intestines.

Jugo de toronja

Avoid drinking large quantities of grapefruit juice (more than 1.2 litres a day). Grapefruit contains compounds that can increase the level of atorvastatin in your blood, which raises your risk of serious side effects like muscle damage.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.