Can I take Ashwagandha and Solifenacin together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking ashwagandha and solifenacin together may increase the risk of side effects such as drowsiness, dizziness, or a dry mouth. Ashwagandha has calming properties that could potentially add to the sedative effects of solifenacin.
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Why this happens
Both substances can affect the central nervous system. Ashwagandha is thought to have GABAergic (calming) effects, while solifenacin is an anticholinergic medication. When used together, their combined effects may lead to increased sleepiness or blurred vision. Additionally, ashwagandha may slightly influence the liver enzymes (CYP3A4) that break down solifenacin, potentially leading to higher levels of the medicine in your body.
What you should do
Use caution if combining these two. If you notice excessive sleepiness, severe dry mouth, constipation, or blurred vision, stop taking the ashwagandha and consult your doctor or pharmacist. It is best to start with a low dose of ashwagandha to see how your body reacts while taking solifenacin.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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